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Phase

Phase 1 2Phase EARLY_PHASE1 1Phase 2/3 1Phase 2 1

Status

Completed 3Withdrawn 1Recruiting 1

Sponsor Class

OTHER 3NIH 1INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 2

Conditions

Glioblastoma 80Brain Neoplasms 34Gliosarcoma 30Glioma 24Astrocytoma 18Central Nervous System Neoplasms 11Medulloblastoma 9Oligodendroglioma 5Neuroblastoma 5Ganglioneuroblastoma 5Ependymoma 4Diffuse Intrinsic Pontine Glioma 4Neoplasms 3Breast Neoplasms 3Meningeal Carcinomatosis 2Melanoma 2Lung Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Untreated Childhood Anaplastic Astrocytoma 1Squamous Cell Carcinoma of Head and Neck 1Spinal Cord Neoplasms 1Sarcoma 1Salivary Gland Neoplasms 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Retinoblastoma 1Recurrence 1Rare Diseases 1Prostatic Neoplasms 1Pinealoma 1

Interventions

Temozolomide 74Radiotherapy 34Carboplatin 21Bevacizumab 18Magnetic Resonance Spectroscopy 17Irinotecan 16Carmustine 16Vincristine 14Surgical Procedures, Operative 13Filgrastim 13Procarbazine 10Erlotinib Hydrochloride 8Cyclophosphamide 8Peripheral Blood Stem Cell Transplantation 7O(6)-benzylguanine 7Lomustine 7Etoposide 7sargramostim 6Imatinib Mesylate 6Flucytosine 6Cisplatin 62-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 6temsirolimus 5Vorinostat 5Thiotepa 5Radiotherapy, Intensity-Modulated 5Radiation 5Immunohistochemistry 5Biopsy 52,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Oligodendroglioma × Radiation × CNS × Clear all
NCT04105374 2026-05-07

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

NRG Oncology

Phase 2/3 Withdrawn
CNS

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT04623931 2026-01-14

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

M.D. Anderson Cancer Center

Phase 2 Recruiting
40 enrolled
CNS

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT01165632 2025-09-02

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

Mayo Clinic

Phase EARLY_PHASE1 Completed
24 enrolled
CNSSarcoma

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Glioma, Subependymal, Gliosarcoma

NCT02871843 2022-05-16

G-FORCE-1

EpicentRx, Inc.

Phase 1 Completed
19 enrolled
CNS

Glioblastoma, Oligodendroglioma

NCT00650923 2014-05-30

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

National Cancer Institute (NCI)

Phase 1 Completed
61 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

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