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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Glioblastoma 41Central Nervous System Neoplasms 32Gliosarcoma 29Brain Neoplasms 28Astrocytoma 28Glioma 20Oligodendroglioma 16Ependymoma 6Medulloblastoma 4Neuroectodermal Tumors, Primitive 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Neuroblastoma 2Neoplasms 2Neoplasm Metastasis 2Meningioma 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, Follicular 2Lymphoma, B-Cell, Marginal Zone 2Lymphoma 2Leukemia, Lymphocytic, Chronic, B-Cell 2Familial ependymoma 2Choroid Plexus Neoplasms 2Burkitt Lymphoma 2Waldenstrom Macroglobulinemia 1Vasculitis, Central Nervous System 1Testicular Neoplasms 1Stiff-Person Syndrome 1

Interventions

Carboplatin 13Temozolomide 11Filgrastim 9Radiotherapy 6Etoposide 6Vincristine 5Irinotecan 4Granulocyte Colony-Stimulating Factor 4etoposide phosphate 3Peripheral Blood Stem Cell Transplantation 3O(6)-benzylguanine 3Ifosfamide 3Busulfan 3Vorinostat 2Topotecan 2Radiotherapy, Intensity-Modulated 2Psychiatric Rehabilitation 2Oxaliplatin 2Melphalan 2Magnetic Resonance Spectroscopy 2Lenalidomide 2Doxorubicin 2Cyproheptadine 2Cyclophosphamide 2Cilengitide 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 2veliparib 1trioctyl phosphine oxide 1tipifarnib 1sodium thiosulfate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Optic Nerve Glioma × Carmustine × CNS × Clear all
NCT00003765 2013-02-05

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

National Cancer Institute (NCI)

Phase 1 Completed
36 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

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