Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Astrocytoma 5Glioma 4Glioblastoma 4Oligodendroglioma 3Neuroblastoma 3Gliosarcoma 3Central Nervous System Neoplasms 3Optic Nerve Glioma 2Brain Neoplasms 2Stomach Neoplasms 1Rhabdoid Tumor 1Prostatic Neoplasms 1Pancreatic Neoplasms 1Neurologic Manifestations 1Neurofibromatosis 1 1Neuroectodermal Tumors, Primitive 1Neoplasm Metastasis 1Multiple Myeloma 1Meningioma 1Melanoma 1Medulloblastoma 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma 1Hematologic Neoplasms 1Familial ependymoma 1Ependymoma 1Diffuse Intrinsic Pontine Glioma 1Colorectal Neoplasms 1Colonic Neoplasms 1Choroid Plexus Neoplasms 1

Interventions

Carboplatin 13Temozolomide 11Filgrastim 9Radiotherapy 6Etoposide 6Vincristine 5Irinotecan 4Granulocyte Colony-Stimulating Factor 4etoposide phosphate 3Peripheral Blood Stem Cell Transplantation 3O(6)-benzylguanine 3Ifosfamide 3Busulfan 3Vorinostat 2Topotecan 2Radiotherapy, Intensity-Modulated 2Psychiatric Rehabilitation 2Oxaliplatin 2Melphalan 2Magnetic Resonance Spectroscopy 2Lenalidomide 2Doxorubicin 2Cyproheptadine 2Cyclophosphamide 2Cilengitide 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 2veliparib 1trioctyl phosphine oxide 1tipifarnib 1sodium thiosulfate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Optic Nerve Glioma × Lenalidomide × CNS × Clear all
NCT01553149 2025-01-07

Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

National Cancer Institute (NCI)

Phase 2 Completed
75 enrolled 17 charts
CNS

Astrocytoma, Neurofibromatosis 1, Optic Nerve Glioma

NCT00100880 2013-09-30

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

National Cancer Institute (NCI)

Phase 1 Completed
45 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

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