Announcements Trials
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Phase

Phase 1 3

Status

Suspended 1Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 3Genitourinary 1Gastrointestinal 1Dermatologic 1

Conditions

Neuroblastoma 12Recurrence 3Osteosarcoma 3Neoplasm Metastasis 3Melanoma 3Brain Neoplasms 3Sarcoma 2Rhabdomyosarcoma 2Rhabdoid Tumor 2Neurofibrosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Lymphoma 2Leukemia, Myelomonocytic, Juvenile 2Leukemia 2Glioma 2Glioblastoma 2Desmoplastic Small Round Cell Tumor 2Breast Neoplasms 2Wilms Tumor 1Uveal Melanoma 1Thyroid Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Sarcoma, Ewing 1Sarcoma, Clear Cell 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pheochromocytoma 1Paraganglioma 1Neurofibromatosis 1 1Neuroendocrine Tumors 1Neuroectodermal Tumors, Primitive 1

Interventions

Cyclophosphamide 10Temozolomide 8X-Rays 7Specimen Handling 7Irinotecan 7Phantoms, Imaging 6Magnetic Resonance Spectroscopy 6Filgrastim 6Carboplatin 5Biopsy 5fludarabine 4Nuclear Medicine Department, Hospital 4olaparib 3fludarabine phosphate 3etoposide phosphate 3dinutuximab 3Zoledronic Acid 3Oxaliplatin 3Nivolumab 3Ifosfamide 3Granulocyte Colony-Stimulating Factor 3Gemcitabine 3Etoposide 3Docetaxel 3ulixertinib 2tipifarnib 2tazemetostat 2selpercatinib 2palbociclib 2lorukafusp alfa 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Osteosarcoma × fludarabine phosphate × CNS × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04539366 2026-05-13

Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, The GD2-CAR PERSIST Trial

National Cancer Institute (NCI)

Phase 1 Suspended
67 enrolled
CNSSarcoma

Neuroblastoma, Osteosarcoma

NCT01953900 2026-04-22

VEGAS

Baylor College of Medicine

Phase 1 Active not recruiting
26 enrolled
CNSSarcoma

Chickenpox, Neuroblastoma, Osteosarcoma

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