Announcements Trials
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Phase

Phase NA 3Phase EARLY_PHASE1 1Phase 1/2 1

Status

Recruiting 2Not yet recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 3NIH 2

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 24Other hematologic neoplasm 8Lymphoid 8Gastrointestinal 6Thoracic 5CNS 5Other 3Head & Neck 3Gynecologic 3Genitourinary 3Sarcoma 1Plasma cell 1Dermatologic 1

Conditions

Brain Neoplasms 635Glioblastoma 566Glioma 405Neuroblastoma 174Neoplasms 123Astrocytoma 106Central Nervous System Neoplasms 103Medulloblastoma 87Breast Neoplasms 86Meningioma 82Carcinoma, Non-Small-Cell Lung 78Melanoma 77Lung Neoplasms 69Sarcoma 66Ependymoma 64Neurofibromatosis 1 63Recurrence 50Oligodendroglioma 48Neoplasm Metastasis 48Osteosarcoma 47Meningeal Carcinomatosis 46Rhabdomyosarcoma 45Diffuse Intrinsic Pontine Glioma 44Pheochromocytoma 43Rhabdoid Tumor 41Paraganglioma 41Gliosarcoma 40Sarcoma, Ewing 39Pancreatic Neoplasms 39Colorectal Neoplasms 33

Interventions

Saline Solution 1Remifentanil 1Methadone 1Extracorporeal Shockwave Therapy 1Dexmedetomidine 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Pain × CNS × 1 year × Clear all
NCT06507748 2026-06-05

A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)

National Institutes of Health Clinical Center (CC)

Phase NA Recruiting
70 enrolled
CNS

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

NCT01362803 2026-06-01

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
99 enrolled 1 FDA
CNS

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

NCT06810336 2026-05-04

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery

University of Virginia

Phase EARLY_PHASE1 Recruiting
40 enrolled
CNS

Brain Injuries, Brain Neoplasms, Pain

NCT07398066 2026-02-09

DEX-NEURO

University of Malaya

Phase NA Not yet recruiting
60 enrolled
CNS

Brain Neoplasms, Delirium, Meningioma, Pain

NCT04320108 2025-06-19

ESWT for Shoulder Pain in Patients With Brain Damage

Bundang CHA Hospital

Phase NA Completed
6 enrolled
CNS

Brain Injuries, Brain Neoplasms, Hypoxia, Brain, Pain, Stroke

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