Announcements Trials
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Phase

Phase NA 1Phase 1/2 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 3CNS 2Other hematologic neoplasm 1Other 1Lymphoid 1Head & Neck 1Gastrointestinal 1

Conditions

Brain Neoplasms 83Glioma 73Glioblastoma 73Neuroblastoma 27Neoplasms 22Astrocytoma 20Neurofibromatosis 1 19Ependymoma 19Sarcoma 18Medulloblastoma 18Central Nervous System Neoplasms 18Rhabdoid Tumor 15Melanoma 15Meningioma 14Carcinoma, Non-Small-Cell Lung 14Osteosarcoma 13Wilms Tumor 12Sarcoma, Ewing 12Rhabdomyosarcoma 12Breast Neoplasms 12Neurofibroma, Plexiform 11Hepatoblastoma 11Diffuse Intrinsic Pontine Glioma 10Neuroectodermal Tumors, Primitive, Peripheral 9Lymphoma, Non-Hodgkin 9Histiocytosis, Langerhans-Cell 9Thyroid Neoplasms 8Recurrence 8Pancreatic Neoplasms 8Neoplasm Metastasis 8

Interventions

AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Pain × CNS × 30 days × Clear all
NCT06507748 2026-06-05

A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)

National Institutes of Health Clinical Center (CC)

Phase NA Recruiting
70 enrolled
CNS

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

NCT01362803 2026-06-01

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
99 enrolled 1 FDA
CNS

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

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