Announcements Trials
Browse Landscape

Phase

Phase 1/2 1Phase 1 1

Status

Recruiting 1Completed 1Approved for marketing 1

Sponsor Class

INDUSTRY 3

Study Type

Interventional 2Expanded_access 1

Sponsor

Cancer Type

Thoracic 5Gastrointestinal 5Other hematologic neoplasm 3Myeloid 3CNS 3Breast 3Other neoplasm 2Endocrine 2NET 1Lymphoid 1Genitourinary 1Dermatologic 1

Conditions

Brain Neoplasms 2306Glioblastoma 2010Glioma 1397Central Nervous System Neoplasms 692Astrocytoma 667Neuroblastoma 647Gliosarcoma 480Neoplasms 405Oligodendroglioma 404Breast Neoplasms 327Medulloblastoma 307Carcinoma, Non-Small-Cell Lung 254Meningioma 229Recurrence 223Sarcoma 214Melanoma 206Neoplasm Metastasis 202Lung Neoplasms 198Ependymoma 198Neurofibromatosis 1 169Lymphoma 161Meningeal Carcinomatosis 138Osteosarcoma 134Ovarian Neoplasms 132Wilms Tumor 123Precursor Cell Lymphoblastic Leukemia-Lymphoma 123Head and Neck Neoplasms 117Lymphoma, Non-Hodgkin 116Diffuse Intrinsic Pontine Glioma 113Rhabdomyosarcoma 106

Interventions

vorasidenib 1glutathione pegylated liposomal doxorubicin 1Trastuzumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Pathologic Processes × CNS × Clear all
NCT07098806 2025-08-01

CA2024-LM-001

Plus Therapeutics

Phase 1 Recruiting
24 enrolled
CNS

Meningeal Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Nervous System Diseases, Nervous System Neoplasms, Pathologic Processes, Central Nervous System Neoplasms, Meningeal Carcinomatosis

NCT05592743 2024-11-05

Vorasidenib Expanded Access Program

Servier

Approved for marketing
CNS

Astrocytoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Oligodendroglioma, Pathologic Processes, Recurrence, Neuroectodermal Tumors, Neoplasms, Neuroepithelial, Disease Attributes

NCT01386580 2015-01-22

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

BBB-Therapeutics B.V.

Phase 1/2 Completed
84 enrolled
BreastCNSDermatologicThoracic

Brain Diseases, Brain Neoplasms, Breast Neoplasms, Central Nervous System Diseases, Glioma, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Neoplastic Processes, Nervous System Diseases, Nervous System Neoplasms, Pathologic Processes, Central Nervous System Neoplasms

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