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Phase

Phase EARLY_PHASE1 1Phase 2 1Phase 1 1

Status

Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1Myeloid 1

Conditions

Neuroblastoma 16Central Nervous System Neoplasms 13Brain Neoplasms 9Medulloblastoma 8Rhabdoid Tumor 6Astrocytoma 6Sarcoma 5Glioma 5Oligodendroglioma 4Lymphoma 4Pinealoma 3Osteosarcoma 3Optic Nerve Glioma 3Ependymoma 3Testicular Neoplasms 2Testicular Germ Cell Tumor 2Teratoma 2Spinal Cord Neoplasms 2Rhabdomyosarcoma 2Recurrence 2Ovarian Neoplasms 2Neuroectodermal Tumors, Primitive, Peripheral 2Neoplasms, Germ Cell and Embryonal 2Neoplasms 2Kidney Neoplasms 2Glioblastoma 2Ganglioneuroblastoma 2Familial ependymoma 2Drug-Related Side Effects and Adverse Reactions 2Choroid Plexus Neoplasms 2

Interventions

Temozolomide 6Cyclophosphamide 5Magnetic Resonance Spectroscopy 4Carboplatin 4etoposide phosphate 3Thiotepa 3Surgical Procedures, Operative 3Irinotecan 3Filgrastim 3Automobiles 3temsirolimus 2fludarabine 2entinostat 2Vincristine 2Radiotherapy, Conformal 2Proton Therapy 2Peripheral Blood Stem Cell Transplantation 2Nivolumab 2Isotretinoin 2Granulocyte Colony-Stimulating Factor 2Gadolinium DTPA 2Etoposide 2Donepezil 2Cisplatin 2Celecoxib 2Bevacizumab 2Amplified Fragment Length Polymorphism Analysis 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 2trametinib 1tozuleristide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Pinealoma × etoposide phosphate × CNS × Clear all
NCT02574728 2026-03-02

AflacST1502

Emory University

Phase 2 Active not recruiting
46 enrolled
CNSMyeloidSarcoma

Brain Neoplasms, Carcinoma, Ependymoma, Histiocytosis, Langerhans-Cell, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

C17 Council

Phase EARLY_PHASE1 Recruiting
15 enrolled
CNS

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT00867178 2022-01-13

Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System

National Cancer Institute (NCI)

Phase 1 Completed
33 enrolled
CNS

Medulloblastoma, Pinealoma

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