Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 1Completed 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 41Lymphoid 41Myeloid 9Plasma cell 5CNS 2Genitourinary 1Gastrointestinal 1Classical hematology 1Breast 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Neuroblastoma 2Leukemia, Myeloid, Acute 2Recurrence 1Neoplasms 1Lymphoma, Non-Hodgkin 1

Interventions

Psychiatric Rehabilitation 7Cyclophosphamide 7Melphalan 6Radiotherapy 5Methylprednisolone 5Flow Cytometry 5Busulfan 5Therapeutics 4Filgrastim 4sargramostim 3Topotecan 3Rituximab 3Polymerase Chain Reaction 3Early Intervention, Educational 3Drug Therapy 3Dexamethasone 3Caspofungin 3Calcium Dobesilate 3Antilymphocyte Serum 3venetoclax 2thymoglobulin 2tanespimycin 2liposomal amphotericin B 2fludarabine 2Vorinostat 2Voriconazole 2Thiotepa 2Peripheral Blood Stem Cell Transplantation 2Ondansetron 2Methylphenidate 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Precursor Cell Lymphoblastic Leukemia-Lymphoma × venetoclax × CNS × Clear all
NCT04029688 2024-12-20

A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors

Hoffmann-La Roche

Phase 1/2 Terminated
38 enrolled 34 charts
CNSLymphoidOther hematologic neoplasm

Neuroblastoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03236857 2023-05-22

A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

AbbVie

Phase 1 Completed
143 enrolled
CNSLymphoidOther hematologic neoplasm

Lymphoma, Non-Hodgkin, Neoplasms, Neuroblastoma, Recurrence, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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