Clinical Trials Browser

INDUSTRY × Recurrence × CNS × Clear all

Neuroblastoma, Recurrence, Ganglioneuroblastoma

NCT02650401 2026-03-25

STARTRK-NG

CNSEndocrineGenitourinaryHead & NeckSarcoma

Thyroid Cancer, Papillary, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Ewing, Central Nervous System Neoplasms, Nephroma, Mesoblastic

NCT05283330 2026-03-20

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

Phase 1 Recruiting

48 enrolled

BreastCNSGastrointestinalGenitourinaryGynecologicThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Glioblastoma, Neoplasm Metastasis, Prostatic Neoplasms, Recurrence, Colorectal Neoplasms

Clinical Trials

DUAL-NK-NB

STARTRK-NG

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

REMASTer: REcurrent Brain Metastases After SRS Trial

A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

Expanded Access Protocol for the Use of SL-28 in the Treatment of Advanced Solid Tumors

Lerapolturev in Recurrent Malignant Glioma

CerebralEDV

PATHWAyS

Safety and Efficacy of Systemic Allogenic NK Cells in R/R Neuroblastoma

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

A Drug-drug Interaction Study of Avapritinib and Midazolam

Vorasidenib Expanded Access Program

CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma

Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients

Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors

A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

PIVOT IO 020

A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma

A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)

A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma

A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors

ANG1005 in Patients With Recurrent High-Grade Glioma

ReACT

Toca5

A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)

A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB

Study Evaluating the Efficacy and Safety With CAR-T for Relapsed or Refractory Neuroblastoma in Children

Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan

Post-approval Study of NovoTTF-100A in Recurrent GBM Patients

Study of AEE788 in Patients With Recurrent/Relapse Glioblastoma Multiforme (GBM)

Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma

Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma

A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma

VEG102857

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM)

Phase 2 Study MPC-6827 for Recurrent Glioblastoma Multiforme

Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients

Phase 1 Study of MPC-6827 and Carboplatin in Recurrent/Relapsed Glioblastoma Multiforme

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

G207 Followed by Radiation Therapy in Malignant Glioma