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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1CNS 1

Conditions

Neuroblastoma 6Osteosarcoma 3Sarcoma, Ewing 2Rhabdomyosarcoma 2Sarcoma, Synovial 1Sarcoma, Clear Cell 1Sarcoma, Alveolar Soft Part 1Sarcoma 1Rhabdoid Tumor 1Recurrence 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Osteoporosis 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Nerve Sheath Neoplasms 1Neoplasms 1Myoepithelioma 1Myelodysplastic Syndromes 1Lymphoma, Non-Hodgkin 1Leukemia, Myeloid, Acute 1Hodgkin Disease 1Gliosarcoma 1Glioma 1Glioblastoma 1Desmoplastic Small Round Cell Tumor 1Chordoma 1Brain Neoplasms 1Astrocytoma 1

Interventions

Cyclophosphamide 2sargramostim 1poly ICLC 1pembrolizumab 1olaparib 1lutetium Lu 177 dotatate 1lorvotuzumab mertansine 1ixabepilone 1fludarabine 1cixutumumab 1aldesleukin 1Zoledronic Acid 1Trabectedin 1Quality of Life 1Patient Reported Outcome Measures 1Molecular Diagnostic Techniques 1Interleukin-2 1Immunotherapy, Adoptive 1Immunotherapy 1Drug Therapy 1Decitabine 1CLR1404 1Biological Therapy 1Ado-Trastuzumab Emtansine 1Adjuvants, Pharmaceutic 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Sarcoma, Synovial × Zoledronic Acid × CNS × Clear all
NCT06625190 2026-03-11

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

University of Florida

Phase 1/2 Recruiting
27 enrolled
CNSSarcoma

Chordoma, Myoepithelioma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Nerve Sheath Neoplasms, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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