Announcements Trials
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Phase

Phase 3 2

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 2CNS 2Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Brain Neoplasms 11Glioblastoma 3Small Cell Lung Carcinoma 2Neoplasm Metastasis 2Lung Neoplasms 2Recurrence 1Neurotoxicity Syndromes 1Neoplasms, Germ Cell and Embryonal 1Melanoma 1Gliosarcoma 1Gastrointestinal Neoplasms 1Epilepsy 1Ependymoma 1Craniopharyngioma 1Cognitive Dysfunction 1Central Nervous System Neoplasms 1Central Nervous System Carcinoma 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1Breast Neoplasms 1

Interventions

Radiosurgery 8Docetaxel 4Cisplatin 4Carboplatin 4Magnetic Resonance Spectroscopy 3Filgrastim 3pembrolizumab 2Specimen Handling 2Radiotherapy 2Paclitaxel 2Nivolumab 2Mental Status and Dementia Tests 2Memantine 2Fluorodeoxyglucose F18 2Etoposide 2temsirolimus 1sargramostim 1sacituzumab govitecan 1regorafenib 1pentetreotide 1pazopanib 1molibresib 1etoposide phosphate 1etirinotecan pegol 1entinostat 1durvalumab 1cc-486 1budigalimab 1berzosertib 1atezolizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Small Cell Lung Carcinoma × Memantine × CNS × Clear all
NCT04588246 2026-05-20

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

NRG Oncology

Phase 3 Terminated
19 enrolled 19 charts
BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT04804644 2026-05-04

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

NRG Oncology

Phase 3 Recruiting
200 enrolled
CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

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