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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Gynecologic 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Glioblastoma 17Gliosarcoma 15Central Nervous System Neoplasms 14Astrocytoma 13Brain Neoplasms 10Glioma 8Oligodendroglioma 7Optic Nerve Glioma 3Medulloblastoma 3Familial ependymoma 3Choroid Plexus Neoplasms 3Ependymoma 2Wilms Tumor 1Testicular Neoplasms 1Teratoma 1Sarcoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma 1

Interventions

Filgrastim 14Carboplatin 11Peripheral Blood Stem Cell Transplantation 9Ifosfamide 9Etoposide 8Flow Cytometry 5Thiotepa 4Therapeutics 4Paclitaxel 4Cyclophosphamide 4Cisplatin 4pegfilgrastim 3Temozolomide 3Psychiatric Rehabilitation 3Polymerase Chain Reaction 3Melphalan 3Granulocyte Colony-Stimulating Factor 3Dexamethasone 3Busulfan 3sargramostim 2liposomal amphotericin B 2ixabepilone 2etoposide phosphate 2aldesleukin 2Topotecan 2Radiotherapy 2Ondansetron 2Methylprednisolone 2Magnetic Resonance Spectroscopy 2Itraconazole 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Testicular Neoplasms × O(6)-benzylguanine × CNS × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

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