Announcements Trials
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Phase

Phase 2 4Phase 1 4Phase 2/3 2Phase NA 1

Status

Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 3Endocrine 3Thoracic 2Plasma cell 2Other hematologic neoplasm 2Myeloid 2Gynecologic 2Gastrointestinal 2CNS 2Lymphoid 1Dermatologic 1

Conditions

Glioblastoma 15Brain Neoplasms 15Glioma 9Neoplasms 6Carcinoma, Non-Small-Cell Lung 6Neoplasms by Site 5Neoplasms by Histologic Type 5Hematologic Neoplasms 5Recurrence 4Neuroblastoma 4Astrocytoma 4Spinal Cord Neoplasms 3Lymphoproliferative Disorders 3Lung Neoplasms 3Colorectal Neoplasms 3Thyroid Carcinoma, Anaplastic 2Thyroid Cancer, Papillary 2Ovarian Neoplasms 2Oligodendroglioma 2Neurofibromatosis 1 2Neoplasm Metastasis 2Multiple Myeloma 2Melanoma 2Medulloblastoma 2Lymphoma 2Laryngeal Neoplasms 2Erdheim-Chester Disease 2Central Nervous System Neoplasms 2cyclopia sequence 1Vitamin D Deficiency 1

Interventions

trametinib 1dabrafenib 1cobimetinib 1Vemurafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Thyroid Carcinoma, Anaplastic × CNS × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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