Announcements Trials
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Phase

Phase 2 2

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 81Thoracic 14Gynecologic 12Gastrointestinal 12Head & Neck 10Genitourinary 9Dermatologic 5Sarcoma 4Other solid neoplasm 2CNS 2Plasma cell 1Other hematologic neoplasm 1Endocrine 1

Conditions

Glioblastoma 85Brain Neoplasms 84Glioma 65Neuroblastoma 30Central Nervous System Neoplasms 24Meningioma 23Medulloblastoma 21Neoplasms 20Sarcoma 19Ependymoma 19Astrocytoma 18Melanoma 17Breast Neoplasms 17Rhabdoid Tumor 15Neurofibromatosis 1 15Wilms Tumor 13Thyroid Neoplasms 12Sarcoma, Ewing 12Rhabdomyosarcoma 12Osteosarcoma 12Hepatoblastoma 12Lung Neoplasms 11Gliosarcoma 11Carcinoma, Non-Small-Cell Lung 11Ovarian Neoplasms 10Neurofibroma, Plexiform 10Recurrence 9Prostatic Neoplasms 9Pancreatic Neoplasms 9Neoplasm Metastasis 9

Interventions

pembrolizumab 2lenvatinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Triple Negative Breast Neoplasms × CNS × 30 days × Clear all
NCT04348747 2026-05-11

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Roswell Park Cancer Institute

Phase 2 Recruiting
23 enrolled
BreastCNS

Brain Neoplasms, Triple Negative Breast Neoplasms

NCT03797326 2026-05-04

LEAP-005

Merck Sharp & Dohme LLC

Phase 2 Completed
611 enrolled 27 charts
BreastCNSGastrointestinalGynecologic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Biliary Tract Neoplasms, Glioblastoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

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