Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

OTHER 11INDUSTRY 10NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 46Gynecologic 12Thoracic 6Genitourinary 6Gastrointestinal 5Dermatologic 3Sarcoma 2Other solid neoplasm 2Head & Neck 2CNS 2Plasma cell 1Other hematologic neoplasm 1

Conditions

Brain Neoplasms 206Glioblastoma 169Central Nervous System Neoplasms 138Astrocytoma 135Gliosarcoma 132Neuroblastoma 109Glioma 104Oligodendroglioma 87Medulloblastoma 68Sarcoma 51Neoplasms 45Ependymoma 43Osteosarcoma 40Wilms Tumor 39Familial ependymoma 38Neuroectodermal Tumors, Primitive, Peripheral 36Optic Nerve Glioma 33Breast Neoplasms 33Lymphoma, Non-Hodgkin 32Neurofibromatosis 1 31Choroid Plexus Neoplasms 29Lymphoma 28Burkitt Lymphoma 28Precursor Cell Lymphoblastic Leukemia-Lymphoma 27Rhabdomyosarcoma 23Rhabdoid Tumor 23Recurrence 21Meningioma 21Carcinoma, Non-Small-Cell Lung 21Testicular Neoplasms 20

Interventions

veliparib 1Platinum 1Irinotecan 1Cisplatin 17-hydroxystaurosporine 11,2-diaminocyclohexaneplatinum II citrate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Triple Negative Breast Neoplasms × CNS × Clear all
NCT02595905 2026-04-08

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

National Cancer Institute (NCI)

Phase 2 Completed
344 enrolled 11 charts
BreastCNS

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00031681 2013-09-30

7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)

National Cancer Institute (NCI)

Phase 1 Completed
41 enrolled
BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Esthesioneuroblastoma, Olfactory, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

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