Announcements Trials
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Phase

Phase 1 2

Status

Enrolling by invitation 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Neurofibromatosis 1 2Neurofibroma 1

Interventions

Temozolomide 166Magnetic Resonance Spectroscopy 130Radiotherapy 97Specimen Handling 81Radiosurgery 60Cyclophosphamide 56pembrolizumab 51Bevacizumab 51Radiation 48Nivolumab 48Carboplatin 36Biopsy 33Irinotecan 29Etoposide 25Vincristine 24Lomustine 24Topotecan 23Ipilimumab 23Blood Specimen Collection 23Cisplatin 22dinutuximab 21fludarabine 19Surgical Procedures, Operative 19Radiotherapy, Intensity-Modulated 19X-Rays 18abemaciclib 16Mental Status and Dementia Tests 16Granulocyte-Macrophage Colony-Stimulating Factor 16Pemetrexed 15Proton Therapy 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Deoxycholic Acid × CNS × 1 year × Clear all
NCT06300502 2026-04-22

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

Massachusetts General Hospital

Phase 1 Enrolling by invitation
15 enrolled
CNS

Neurofibroma, Neurofibromatosis 1

NCT06132165 2025-11-21

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Massachusetts General Hospital

Phase 1 Completed
13 enrolled
CNS

Neurofibromatosis 1

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