Announcements Trials
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Phase

Phase 2 2Phase 4 1Phase 3 1Phase 1 1

Status

Active not recruiting 2Withdrawn 1Recruiting 1Completed 1

Sponsor Class

OTHER 4NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Lymphoid 84Other hematologic neoplasm 81Myeloid 14Genitourinary 6Sarcoma 5CNS 5Thoracic 3Head & Neck 3Classical hematology 3Plasma cell 2Other solid neoplasm 2Gynecologic 2Breast 2Other neoplasm 1Dermatologic 1

Conditions

Medulloblastoma 4Central Nervous System Neoplasms 2Rhabdoid Tumor 1Ependymoma 1Choroid Plexus Neoplasms 1Brain Neoplasms 1

Interventions

Temozolomide 165Magnetic Resonance Spectroscopy 130Radiotherapy 95Specimen Handling 80Radiosurgery 60Cyclophosphamide 55pembrolizumab 51Bevacizumab 51Nivolumab 48Radiation 47Carboplatin 34Biopsy 33Irinotecan 29Lomustine 25Etoposide 25Vincristine 23Topotecan 23Ipilimumab 23dinutuximab 21Cisplatin 21Blood Specimen Collection 21fludarabine 19Radiotherapy, Intensity-Modulated 19X-Rays 18Surgical Procedures, Operative 18abemaciclib 16Mental Status and Dementia Tests 16Granulocyte-Macrophage Colony-Stimulating Factor 16Pemetrexed 15atezolizumab 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Methotrexate × CNS × 1 year × Clear all
NCT02875314 2026-06-03

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

Nationwide Children's Hospital

Phase 4 Active not recruiting
250 enrolled
CNS

Medulloblastoma

NCT00602667 2026-05-19

Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
293 enrolled 89 charts
CNS

Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor

NCT05535166 2026-02-12

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

St. Jude Children's Research Hospital

Phase 2 Recruiting
130 enrolled
CNS

Brain Neoplasms, Medulloblastoma

NCT00336024 2026-01-23

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Children's Oncology Group

Phase 3 Completed
91 enrolled 24 charts
CNS

Medulloblastoma

NCT06466798 2026-01-08

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

The University of Texas Health Science Center, Houston

Phase 1 Withdrawn
CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

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