Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 1/2 1

Status

Recruiting 2Active not recruiting 2

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 95Other hematologic neoplasm 51CNS 4Plasma cell 3Myeloid 2Dermatologic 2Head & Neck 1Genitourinary 1Classical hematology 1

Conditions

Glioblastoma 2Brain Neoplasms 2Primary Central Nervous System Lymphoma (PCNSL) 1Neurologic Manifestations 1Neuroectodermal Tumors, Primitive 1Medulloblastoma 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma 1Ependymoma 1Central Nervous System Neoplasms 1

Interventions

Temozolomide 165Magnetic Resonance Spectroscopy 130Radiotherapy 95Specimen Handling 80Radiosurgery 60Cyclophosphamide 55pembrolizumab 51Bevacizumab 51Nivolumab 48Radiation 47Carboplatin 34Biopsy 33Irinotecan 29Lomustine 25Etoposide 25Vincristine 23Topotecan 23Ipilimumab 23dinutuximab 21Cisplatin 21Blood Specimen Collection 21fludarabine 19Radiotherapy, Intensity-Modulated 19X-Rays 18Surgical Procedures, Operative 18abemaciclib 16Mental Status and Dementia Tests 16Granulocyte-Macrophage Colony-Stimulating Factor 16Pemetrexed 15atezolizumab 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
ibrutinib × CNS × 1 year × Clear all
NCT07082868 2026-05-06

A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)

Memorial Sloan Kettering Cancer Center

Phase 1 Recruiting
26 enrolled
CNSLymphoid

Primary Central Nervous System Lymphoma (PCNSL)

NCT05106296 2026-01-09

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Augusta University

Phase 1 Recruiting
37 enrolled
CNS

Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT03535350 2025-09-30

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Case Comprehensive Cancer Center

Phase 1 Active not recruiting
36 enrolled
CNS

Brain Neoplasms, Glioblastoma

NCT04446962 2025-09-25

LOC-R01

Institut Curie

Phase 1/2 Active not recruiting
118 enrolled
CNSLymphoid

Lymphoma, Neurologic Manifestations, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms

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