Clinical Trials Browser

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT03975829 2026-04-02

Pediatric Long-Term Follow-up and Rollover Study

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Histiocytosis, Langerhans-Cell, Neuroblastoma, Neurofibromatosis 1, Oligodendroglioma, Ganglioglioma, Neurocytoma, Neurofibroma, Plexiform

NCT03340506 2026-04-01

Dabrafenib and/or Trametinib Rollover Study

Phase 4 Recruiting

100 enrolled

CNSDermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Glioma, Lung Neoplasms, Melanoma

NCT04266665 2026-03-25

Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome

Phase 4 Completed

56 enrolled

CNS

Neuroinflammatory Diseases, Hypoxia, Brain Neoplasms

NCT07486713 2026-03-20

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

Phase 4 Recruiting

16 enrolled

CNSGastrointestinalOther hematologic neoplasm

Glioma, Neoplasms, Leukemia, Myeloid, Acute, Cholangiocarcinoma

NCT06377371 2026-02-27

Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATE

Phase 4 Recruiting

20 enrolled

CNS

Meningioma

NCT05376878 2026-02-23

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Phase 4 Recruiting

10 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT02875314 2026-02-12

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

Phase 4 Active not recruiting

250 enrolled

CNS

Medulloblastoma

NCT06625047 2025-12-31

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

Phase 4 Completed

30 enrolled

CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT06230055 2025-11-25

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Phase 4 Recruiting

37 enrolled

CNS

Meningeal Carcinomatosis

NCT06072807 2025-11-24

Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer

Phase 4 Recruiting

20 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT04081701 2025-11-21

DOMINO-START

Phase 4 Recruiting

200 enrolled

CNSEndocrine

Medulloblastoma, Meningioma, Paraganglioma, Pituitary Neoplasms, Central Nervous System Neoplasms, Esthesioneuroblastoma, Olfactory, Hemangioblastoma

NCT07225101 2025-11-05

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

Phase 4 Recruiting

160 enrolled

CNS

Brain Injuries, Traumatic, Hemorrhagic Stroke, Brain Neoplasms

NCT05342883 2025-09-05

GESTALT

Phase 4 Active not recruiting

61 enrolled

CNS

Glioblastoma, Glioma, Neoplasms

NCT02670161 2025-08-24

Quality Improvement and Practice Based Research in Neurology Using the EMR

Phase 4 Enrolling by invitation

3,300 enrolled

CNS

Brain Concussion, Brain Neoplasms, Epilepsy, Migraine Disorders, Multiple Sclerosis, Parkinson Disease, Restless Legs Syndrome, Stroke, Cognitive Dysfunction

NCT07092202 2025-07-29

Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases

Phase 4 Recruiting

40 enrolled

CNS

Meningeal Carcinomatosis

NCT05702944 2025-06-12

The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma

Phase 4 Recruiting

24 enrolled

CNSEndocrine

Paraganglioma, Pheochromocytoma

Clinical Trials

Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

Pediatric Long-Term Follow-up and Rollover Study

Dabrafenib and/or Trametinib Rollover Study

Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATE

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer

DOMINO-START

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

GESTALT

Quality Improvement and Practice Based Research in Neurology Using the EMR

Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases

The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma