Announcements Trials
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Phase

Phase 3 2Phase 2 1Phase 1/2 1Phase 1 1

Status

Completed 4Terminated 1No longer available 1

Sponsor Class

INDUSTRY 6

Study Type

Interventional 5Expanded_access 1

Sponsor

Cancer Type

CNS 6Sarcoma 1Lymphoid 1

Conditions

Glioblastoma 6Brain Neoplasms 2Neoplasms 1Lymphoma, Follicular 1Gliosarcoma 1Glioma 1Disease 1

Interventions

Temozolomide 123Radiotherapy 47Bevacizumab 46Lomustine 25Radiation 20Nivolumab 17Irinotecan 16Carboplatin 16Cyclophosphamide 14Granulocyte-Macrophage Colony-Stimulating Factor 13pembrolizumab 11dabrafenib 10Trastuzumab 10Surgical Procedures, Operative 10Capecitabine 10paclitaxel-Angiopep-2 conjugate 8TIC10 compound 8Paclitaxel 8Gemcitabine 8Carmustine 8trametinib 7Topotecan 7IL13-PE38 7Everolimus 7Drug Therapy 7Aminolevulinic Acid 7AZD 6244 73-Iodobenzylguanidine 7fludarabine 6enzastaurin 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
INDUSTRY × ABT-414 × CNS × Clear all
NCT02573324 2023-05-11

Intellance1

AbbVie

Phase 3 Completed
691 enrolled 28 charts
CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT03419403 2021-04-14

UNITE Study: Understanding New Interventions With GBM ThErapy

AbbVie

Phase 3 Terminated
40 enrolled 16 charts
CNS

Glioblastoma, Neoplasms

NCT02590263 2020-09-03

Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma

AbbVie

Phase 1/2 Completed
53 enrolled
CNSLymphoid

Glioblastoma, Glioma, Lymphoma, Follicular

NCT02343406 2020-05-22

INTELLANCE-2

AbbVie

Phase 2 Completed
266 enrolled 23 charts
CNS

Brain Neoplasms, Glioblastoma

NCT03123952 2019-07-15

Expanded Access to ABT-414

AbbVie

No longer available
CNS

Disease, Glioblastoma

NCT01800695 2017-11-21

Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme

AbbVie

Phase 1 Completed
202 enrolled
CNS

Glioblastoma

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