Announcements Trials
Browse Landscape

Phase

Phase 1 5Phase 2 1

Status

Terminated 2Completed 2Active not recruiting 2

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

Gastrointestinal 28Plasma cell 13Other hematologic neoplasm 12Myeloid 8Thoracic 6Genitourinary 6CNS 6Tumor-Agnostic 5Sarcoma 5Dermatologic 4Classical hematology 4Breast 4Lymphoid 3Other 2Gynecologic 2Endocrine 1

Conditions

Glioblastoma 5Glioma 2Oligodendroglioma 1Gliosarcoma 1Astrocytoma 1

Interventions

Temozolomide 623Radiotherapy 411Bevacizumab 257Magnetic Resonance Spectroscopy 227Cyclophosphamide 179Radiosurgery 163Carboplatin 160Etoposide 132Radiation 129Vincristine 115Irinotecan 115Cisplatin 103Filgrastim 100Specimen Handling 90Nivolumab 88pembrolizumab 84Surgical Procedures, Operative 83Lomustine 83Topotecan 73Doxorubicin 61Melphalan 59Carmustine 57Radiotherapy, Intensity-Modulated 56sargramostim 53Isotretinoin 53Peripheral Blood Stem Cell Transplantation 52Granulocyte Colony-Stimulating Factor 51Chemotherapy, Adjuvant 51Blood Specimen Collection 51Erlotinib Hydrochloride 50

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Ascorbic Acid × CNS × Clear all
NCT02344355 2025-12-12

A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

University of Iowa

Phase 2 Active not recruiting
90 enrolled
CNS

Glioblastoma

NCT04900792 2025-12-03

XACT-Fe-GBM-01

University of Iowa

Phase 1 Active not recruiting
17 enrolled
CNS

Glioblastoma

NCT01752491 2024-12-20

A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme

University of Iowa

Phase 1 Completed
13 enrolled
CNS

Glioblastoma

NCT02168270 2023-11-24

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

University of Nebraska

Phase 1 Terminated
4 enrolled 6 charts
CNSSarcoma

Astrocytoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT02833701 2023-10-24

Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma

University of Nebraska

Phase 1 Terminated
9 enrolled
CNS

Glioblastoma, Glioma

NCT01891747 2022-03-10

A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma

Vanderbilt-Ingram Cancer Center

Phase 1 Completed
14 enrolled
CNS

Glioma

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