Clinical Trials

Glioblastoma

NCT04222062 2025-02-27

A Study Comparing GLIADEL to Stereotactic Radiosurgery in Metastatic Brain Disease

Phase 2 Recruiting

100 enrolled

Brain Neoplasms

NCT00669669 2022-05-18

O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas

Phase 1/2 Terminated

12 enrolled 13 charts

CNSDermatologicGenitourinaryLymphoidOther hematologic neoplasmPlasma cellSarcoma

Glioblastoma, Gliosarcoma

NCT00536601 2021-04-22

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

Phase NA Completed

174 enrolled 17 charts

Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Burkitt Lymphoma, Hodgkin Disease, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Neuroblastoma, Recurrence, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Neuroectodermal Tumors, Primitive, Peripheral, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating, Intraocular Lymphoma

NCT04755023 2021-02-15

TEMOBIC

53 enrolled

Astrocytoma, Oligodendroglioma

NCT00795665 2020-05-12

Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma

7 enrolled 4 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00984438 2019-11-25

Surgery With Implantable Biodegradable Carmustine (BCNU) Wafer Followed by Chemo for Patients With Recurrent Glioblastoma Multiforme

Phase 1/2 Withdrawn

Glioblastoma

NCT01186406 2019-02-15

Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM)

Phase 2 Terminated

41 enrolled 9 charts

Glioblastoma, Glioma, Gliosarcoma

NCT00003176 2018-06-27

Temozolomide and Carmustine in Treating Patients With Anaplastic Glioma

82 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT02348255 2018-01-09

NovoTTF-100A With Bevacizumab and Carmustine in Treating Patients With Glioblastoma Multiforme in First Relapse

Phase 2 Withdrawn

Brain Neoplasms

NCT01310868 2017-10-05

Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma

59 enrolled 8 charts

Glioblastoma, Gliosarcoma

NCT00003996 2016-12-07

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

93 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00027612 2016-12-07

Irinotecan Plus Radiation Therapy Followed By Chemotherapy in Treating Patients With Glioblastoma Multiforme

Phase 1/2 Completed

58 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003621 2016-07-14

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma

29 enrolled

Astrocytoma, Central Nervous System Neoplasms

NCT00003484 2015-04-23

Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors

21 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00005081 2014-08-21

Carmustine Plus O6-benzylguanine in Treating Patients With Recurrent or Progressive Glioma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00362921 2014-07-10

Gliadel Wafer and O6-Benzylguanine in Treating Patients With Recurrent Glioblastoma Multiforme

52 enrolled

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00002988 2013-06-20

Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma

36 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003467 2013-06-20

Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma

68 enrolled

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00014573 2013-04-08

Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer

Familial ependymoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00046878 2013-03-28

Carmustine and O(6)-Benzylguanine in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Phase 2 Withdrawn

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00002986 2013-02-20

Chemotherapy in Treating Patients With Recurrent Malignant Glioma

36 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003348 2013-02-20

Carmustine Plus O(6)-Benzylguanine in Treating Patients With Recurrent or Progressive Gliomas of the Brain

56 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003463 2013-02-18

Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas

CNSLymphoidOther hematologic neoplasmSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003567 2010-06-11

Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Phase 1 Terminated

8 enrolled

Astrocytoma, Brain Neoplasms, Burkitt Lymphoma, Ependymoma, Glioblastoma, Glioma, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Oligodendroglioma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00548938 2009-09-18

Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM

Phase 2 Terminated

40 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT00283543 2007-10-31

Radiation With Concomitant and Then Sequential Temozolomide in Malignant Glioma

Phase 2 Unknown

40 enrolled