Announcements Trials
Browse Landscape

Phase

Phase 1 4Phase 1/2 2Phase 2 1

Status

Active not recruiting 2Unknown 1Completed 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Thoracic 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Glioma 3Glioblastoma 3Pancreatic Neoplasms 1Oligodendroglioma 1Melanoma 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Breast Neoplasms 1Brain Neoplasms 1Astrocytoma 1

Interventions

Temozolomide 147Radiotherapy 91Cyclophosphamide 53Magnetic Resonance Spectroscopy 43Radiation 42Bevacizumab 38Irinotecan 34Filgrastim 29Radiosurgery 27Specimen Handling 25Nivolumab 25Carboplatin 24Topotecan 23Etoposide 22fludarabine 20Surgical Procedures, Operative 20pembrolizumab 19Vorinostat 18Vincristine 18Melphalan 17Granulocyte Colony-Stimulating Factor 17sargramostim 15Peripheral Blood Stem Cell Transplantation 14Ipilimumab 14Drug Therapy 13temsirolimus 12Sirolimus 12Radiotherapy, Intensity-Modulated 12O(6)-benzylguanine 12Everolimus 12

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Chlorotoxin × CNS × Clear all
NCT05627323 2026-01-29

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

Chimeric Therapeutics

Phase 1 Active not recruiting
42 enrolled
CNS

Glioblastoma

NCT04214392 2025-10-06

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

City of Hope Medical Center

Phase 1 Active not recruiting
19 enrolled
CNS

Glioblastoma, Glioma

NCT00591058 2009-07-17

Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma

TransMolecular

Phase 1 Unknown
36 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00379132 2009-03-31

131-I-TM-601 Study in Adults With Solid Tumors

TransMolecular

Phase 1 Completed
60 enrolled
BreastCNSDermatologicGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioma, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

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