Clinical Trials Browser

Completed × Everolimus × CNS × Clear all

NCT03834740 2025-05-30

A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection

Phase EARLY_PHASE1 Completed

27 enrolled 17 charts

Brain Neoplasms, Glioblastoma, Glioma

NCT02332902 2023-12-20

DCLNF1

Phase 2 Completed

24 enrolled 4 charts

Neurofibroma, Neurofibromatosis 1

NCT03245151 2023-08-30

Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors

Phase 1/2 Completed

64 enrolled 29 charts

Glioma, Recurrence, Rhabdomyosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT00387400 2023-08-04

Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02333565 2023-05-25

CEVOREM

Phase 2 Completed

Meningioma

NCT03355794 2023-01-13

A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

Phase 1 Completed

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT01062399 2022-06-09

RTOG 0913

Phase 1/2 Completed

279 enrolled 14 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01434602 2022-06-01

Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas

Phase 1/2 Completed

86 enrolled 24 charts

Brain Neoplasms, Glioblastoma

NCT00805961 2021-12-08

RT, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in First-line Treatment of GBM

Phase 2 Completed

68 enrolled 8 charts

Glioblastoma

NCT03387020 2021-08-27

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Phase 1 Completed

22 enrolled 16 charts

Familial ependymoma, Diffuse Intrinsic Pontine Glioma, Glioma, Medulloblastoma, Rhabdoid Tumor

NCT00823459 2020-07-28

Everolimus in Treating Patients With Recurrent Low-Grade Glioma

Phase 2 Completed

58 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma

NCT01880749 2020-05-13

Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

Phase EARLY_PHASE1 Completed

Meningioma, Neuroma, Acoustic, Neurofibromatosis 2

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

122 enrolled 11 charts

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01158651 2020-02-05

NFC-RAD001

Phase 2 Completed

23 enrolled 11 charts

Glioma

NCT01305941 2018-12-17

A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases

Phase 2 Completed

32 enrolled 19 charts

Brain Neoplasms, Breast Neoplasms

NCT00782626 2018-08-15

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

Phase 2 Completed

23 enrolled 6 charts

Astrocytoma, Glioma

NCT01419639 2017-07-18

Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2

Phase 2 Completed

10 enrolled 4 charts

Ependymoma, Meningioma, Neurofibromatosis 2

NCT01490476 2017-05-23

AFINF2

Phase 2 Completed

Vestibulocochlear Nerve Diseases, Neuroma, Acoustic, Otorhinolaryngologic Diseases, Peripheral Nervous System Diseases, Neurofibromatosis 2

NCT00790400 2017-02-17

EXIST-2

Phase 3 Completed

118 enrolled 15 charts

Tuberous Sclerosis 2, Astrocytoma, Hereditary Sensory and Autonomic Neuropathies, Seizures, Tuberous Sclerosis, Lymphangioleiomyomatosis, Angiomyolipoma

NCT01204476 2016-07-15

Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma

Phase 1 Completed

CNSDermatologicEndocrine

Glucagonoma, Insulinoma, Paraganglioma, Somatostatinoma, Zollinger-Ellison Syndrome, Carcinoma, Merkel Cell, Carcinoma, Medullary

NCT00789828 2016-02-03

EXIST-1

Phase 3 Completed

117 enrolled 15 charts

Astrocytoma, Tuberous Sclerosis

NCT00085566 2016-01-20

Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer

Phase 1/2 Completed

61 enrolled 8 charts

CNSGenitourinarySarcoma

Brain Neoplasms, Glioblastoma, Prostatic Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT00756340 2015-10-14

A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors

Phase 1 Completed

Recurrence, Central Nervous System Neoplasms

NCT01152827 2015-05-20

PheoCarcRAD001

Phase 2 Completed

Paraganglioma, Extra-Adrenal, Pheochromocytoma

NCT00187174 2015-03-04

Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors

Phase 1 Completed

Brain Neoplasms, Neoplasms, Recurrence, Rhabdomyosarcoma, Sarcoma

NCT00411619 2014-10-20

Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex

Phase 1/2 Completed

28 enrolled 7 charts

Astrocytoma, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT00107237 2013-06-12

AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme

Phase 1/2 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00613132 2013-02-20

Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01637194 2012-07-11

Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer

Phase 1 Completed

CNSGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Colonic Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Esthesioneuroblastoma, Olfactory