Announcements Trials
Browse Landscape

Phase

Phase 2 4Phase EARLY_PHASE1 1Phase 3 1

Status

Completed 72Terminated 10Unknown 9Recruiting 6Withdrawn 2Active not recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

Other hematologic neoplasm 17Lymphoid 9Myeloid 6CNS 6Classical hematology 4Sarcoma 3Plasma cell 2Breast 2Thoracic 1Other solid neoplasm 1Gynecologic 1Dermatologic 1

Conditions

Neuroblastoma 2Medulloblastoma 2Glioblastoma 2Rhabdoid Tumor 1Pyloric Stenosis, Hypertrophic 1Pinealoma 1Neuroectodermal Tumors, Primitive 1Glioma 1Central Nervous System Neoplasms 1Brain Neoplasms 1

Interventions

Temozolomide 79Magnetic Resonance Spectroscopy 68Specimen Handling 45Radiotherapy 42Bevacizumab 29Radiosurgery 27Cyclophosphamide 27Radiation 20pembrolizumab 19Blood Specimen Collection 19fludarabine 16Nivolumab 16Irinotecan 15Carboplatin 13Biopsy 13Etoposide 12Vincristine 11Pemetrexed 11Lomustine 11dinutuximab 9Surgical Procedures, Operative 9trametinib 8abemaciclib 8Ipilimumab 8naxitamab 7fluciclovine F-18 7Watchful Waiting 7Topotecan 7Proton Therapy 7Magnetic Resonance Imaging 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Recruiting × Filgrastim × CNS × Clear all
NCT06528691 2026-05-13

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

St. Jude Children's Research Hospital

Phase 2 Recruiting
52 enrolled
CNS

Glioma, Central Nervous System Neoplasms

NCT06649851 2026-05-05

G-CSF After Chemo-radiation in Patients With Glioblastoma

Massachusetts General Hospital

Phase 2 Recruiting
60 enrolled
CNS

Glioblastoma

NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

C17 Council

Phase EARLY_PHASE1 Recruiting
15 enrolled
CNS

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT05535166 2026-02-12

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

St. Jude Children's Research Hospital

Phase 2 Recruiting
130 enrolled
CNS

Brain Neoplasms, Medulloblastoma

NCT05052957 2025-11-21

hSTAR GBM

Case Comprehensive Cancer Center

Phase 2 Recruiting
16 enrolled
CNS

Glioblastoma

NCT01704716 2020-10-23

High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)

St. Anna Kinderkrebsforschung

Phase 3 Recruiting
3,300 enrolled
CNS

Neuroblastoma

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