Announcements Trials
Browse Landscape

Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Recruiting 2Unknown 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 5

Study Type

Interventional 4Observational 1

Sponsor

Cancer Type

Gastrointestinal 105Thoracic 55Head & Neck 22Other solid neoplasm 13Breast 13Tumor-Agnostic 9Lymphoid 9Genitourinary 8Dermatologic 8Other hematologic neoplasm 6Sarcoma 5Gynecologic 5CNS 5Myeloid 1

Conditions

Glioma 2Meningeal Carcinomatosis 1Glioblastoma 1Diffuse Intrinsic Pontine Glioma 1Carcinoma, Non-Small-Cell Lung 1Brain Neoplasms 1Astrocytoma 1

Interventions

Temozolomide 400Radiotherapy 239Bevacizumab 185Magnetic Resonance Spectroscopy 168Radiosurgery 142Cyclophosphamide 95Irinotecan 79Carboplatin 79Etoposide 78Radiation 76pembrolizumab 70Nivolumab 59Surgical Procedures, Operative 57Filgrastim 56Specimen Handling 53Cisplatin 50Blood Specimen Collection 46Topotecan 45Vincristine 43Melphalan 38Radiotherapy, Intensity-Modulated 36Pemetrexed 36Lomustine 36Ipilimumab 36Everolimus 35Magnetic Resonance Imaging 34Erlotinib Hydrochloride 34Drug Therapy 34Surveys and Questionnaires 33sargramostim 30

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
OTHER × Immune Checkpoint Inhibitors × CNS × Clear all
NCT06431685 2026-05-08

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

Sichuan University

Phase 1 Recruiting
10 enrolled
CNS

Meningeal Carcinomatosis

NCT04943848 2026-03-17

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Ann & Robert H Lurie Children's Hospital of Chicago

Phase 1 Recruiting
36 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Glioma

NCT04225039 2025-08-15

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma

University of Pennsylvania

Phase 2 Active not recruiting
39 enrolled 10 charts
CNS

Glioblastoma

NCT03879512 2024-09-19

Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG

Wuerzburg University Hospital

Phase 1/2 Completed
24 enrolled
CNS

Astrocytoma, Glioma

NCT05638425 2022-12-06

Radiotherapy Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of NSCLC Patients With Symptomatic Brain Metastases

Xiangya Hospital of Central South University

Unknown
20 enrolled
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

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