Clinical Trials Browser

Lapatinib × CNS × Clear all

NCT02101905 2024-11-06

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01622868 2023-10-17

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

Phase 2 Completed

143 enrolled 24 charts

Brain Neoplasms, Breast Neoplasms

NCT00863122 2021-01-12

Concentration and Activity of Lapatinib in Vestibular Schwannomas

Phase EARLY_PHASE1 Completed

26 enrolled 9 charts

Neuroma, Acoustic, Neurofibromatosis 2

NCT00883688 2020-08-26

Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma

Phase 2 Completed

24 enrolled 5 charts

Brain Neoplasms, Ependymoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal

NCT00263588 2019-12-12

Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer

Phase 2 Completed

242 enrolled 19 charts

Brain Neoplasms, Breast Neoplasms, Neoplasms

NCT00820222 2019-04-02

Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast Cancer

Phase 3 Completed

540 enrolled 18 charts

Brain Neoplasms, Breast Neoplasms

NCT00826241 2019-03-22

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

Phase 2 Completed

58 enrolled 11 charts

Brain Neoplasms, Ependymoma, Spinal Cord Neoplasms

NCT00107003 2018-07-05

GW572016 to Treat Recurrent Malignant Brain Tumors

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Gliosarcoma

NCT00973739 2016-03-22

Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Phase 2 Completed

21 enrolled 8 charts

Neurilemmoma, Neuroma, Acoustic, Neurofibromatosis 2

NCT00437073 2015-10-15

Brain Metastases In ErbB2-Positive Breast Cancer

Phase 2 Terminated

22 enrolled 8 charts

Brain Neoplasms, Breast Neoplasms

NCT01218529 2014-12-31

Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors

Phase 2 Completed

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT00313599 2014-07-02

Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

BreastCNSGastrointestinalGenitourinaryGynecologicThoracic

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Dysgerminoma, Esophageal Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Central Nervous System Neoplasms

NCT01077648 2014-05-26

Brain Metastasis in Breast Cancer Patients

Brain Neoplasms, Breast Neoplasms, Neoplasms

NCT00095940 2014-05-23

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

Phase 1/2 Completed

52 enrolled 17 charts

Familial ependymoma, Astrocytoma, Glioblastoma, Medulloblastoma, Oligodendroglioma

NCT00470847 2014-05-22

Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer

Phase 1 Completed

35 enrolled 10 charts

Brain Neoplasms, Breast Neoplasms

NCT00099060 2014-01-27

Lapatinib in Treating Patients With Recurrent Glioblastoma Multiforme

Phase 1/2 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00795678 2013-08-02

Chemotherapeutic Agents in Brain/Breast

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT00098605 2013-06-06

Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases

Phase 2 Completed

Brain Neoplasms, Breast Neoplasms, Breast Neoplasms, Male

NCT00350727 2013-04-19

VEG102857

Phase 2 Completed

75 enrolled 45 charts

Glioblastoma, Glioma, Recurrence

NCT00967031 2013-01-18

Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases

Phase 2 Completed

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT00614978 2012-09-19

LAPTEM

Phase 1 Completed

Brain Neoplasms, Breast Neoplasms