Announcements Trials
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Phase

Phase 1 2Phase NA 1

Status

Completed 2Suspended 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Head & Neck 2Lymphoid 1

Conditions

Neurofibromatosis 1 3Neurofibromatoses 1

Interventions

Temozolomide 623Radiotherapy 411Bevacizumab 257Magnetic Resonance Spectroscopy 227Cyclophosphamide 179Radiosurgery 163Carboplatin 160Etoposide 132Radiation 129Vincristine 115Irinotecan 115Cisplatin 103Filgrastim 100Specimen Handling 90Nivolumab 88pembrolizumab 84Surgical Procedures, Operative 83Lomustine 83Topotecan 73Doxorubicin 61Melphalan 59Carmustine 57Radiotherapy, Intensity-Modulated 56sargramostim 53Isotretinoin 53Peripheral Blood Stem Cell Transplantation 52Granulocyte Colony-Stimulating Factor 51Chemotherapy, Adjuvant 51Blood Specimen Collection 51Erlotinib Hydrochloride 50

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Lasers, Solid-State × CNS × Clear all
NCT06934928 2026-06-04

Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs)

Massachusetts General Hospital

Phase NA Suspended
10 enrolled
CNS

Neurofibromatosis 1, Neurofibromatoses

NCT06132165 2025-11-21

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Massachusetts General Hospital

Phase 1 Completed
13 enrolled
CNS

Neurofibromatosis 1

NCT04730583 2025-02-21

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

Massachusetts General Hospital

Phase 1 Completed
34 enrolled
CNS

Neurofibromatosis 1

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