Clinical Trials Browser

Phase 2 × Lomustine × CNS × Clear all

NCT06325683 2026-05-26

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Phase 2 Suspended

Glioblastoma

NCT02724579 2026-05-20

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Phase 2 Active not recruiting

Medulloblastoma

NCT06336291 2026-04-21

GLIOSTELLA

Phase 2 Active not recruiting

Glioblastoma

NCT04762069 2026-04-15

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Phase 2 Active not recruiting

Brain Neoplasms, Glioblastoma

NCT03678883 2026-04-03

9-ING-41 in Patients With Advanced Cancers

Phase 2 Active not recruiting

BreastCNSGastrointestinalGenitourinaryLymphoidOther hematologic neoplasmSarcomaThoracic

Bone Neoplasms, Breast Neoplasms, Glioma, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms, Leukemia-Lymphoma, Adult T-Cell

NCT04049669 2026-01-08

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Phase 2 Active not recruiting

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma

NCT01582269 2025-11-24

A Study in Recurrent Glioblastoma (GB)

Phase 2 Completed

158 enrolled 20 charts

Glioblastoma

NCT04402073 2025-10-23

PersoMed-I

Phase 2 Terminated

Medulloblastoma

NCT04863950 2025-08-27

Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma

Phase 2 Recruiting

Glioblastoma

NCT06177964 2025-08-17

Lerapolturev (PVSRIPO) in GBM

Phase 2 Recruiting

Glioblastoma, Glioma

NCT07120984 2025-08-13

IMAGLIO

Phase 2 Not yet recruiting

Glioma

NCT02986178 2025-07-11

Lerapolturev in Recurrent Malignant Glioma

Phase 2 Completed

121 enrolled 15 charts

Brain Neoplasms, Glioblastoma, Glioma, Recurrence

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Phase 2 Completed

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT02926222 2022-09-09

REGOMA

Phase 2 Completed

Glioblastoma

NCT03022578 2022-08-10

Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Phase 2 Terminated

7 enrolled 9 charts

Astrocytoma, Glioblastoma

NCT02343406 2020-05-22

INTELLANCE-2

Phase 2 Completed

266 enrolled 23 charts

Brain Neoplasms, Glioblastoma

NCT01067469 2020-03-17

Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)

Phase 2 Completed

83 enrolled 15 charts

Brain Neoplasms, Glioblastoma

NCT00031590 2019-04-25

Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma

Phase 2 Terminated

30 enrolled 5 charts

Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT01562197 2019-01-24

AxiGII

Phase 2 Completed

Glioblastoma, Recurrence

NCT01860638 2018-04-30

A Comparison of Continuous Bevacizumab (Avastin) Treatment or Placebo in Addition to Lomustine Followed by Standard of Care After Disease Progression in Participants With Glioblastoma

Phase 2 Completed

Glioblastoma

NCT00002806 2016-07-13

Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma

Phase 2 Completed

Astrocytoma, Central Nervous System Neoplasms

NCT00431561 2013-12-03

Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Camurati-Engelmann Syndrome, Glioblastoma, Neoplasms

NCT00276666 2013-09-17

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Metastatic Medulloblastoma Who Have Undergone Surgery

Phase 2 Unknown

Central Nervous System Neoplasms

NCT00274911 2013-08-02

Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors

Phase 2 Unknown

Central Nervous System Neoplasms

NCT00003101 2013-06-25

Combination Chemotherapy and Bone Marrow Transplantation or Peripheral Stem Cell Transplantation in Treating Patients With Oligodendroglioma

Phase 2 Completed

Oligodendroglioma, Central Nervous System Neoplasms

NCT01737346 2012-12-03

Procarbazine and Lomustine in Recurrent Glioblastoma

Phase 2 Unknown

Glioblastoma, Recurrence

NCT00504660 2012-01-11

6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients

Phase 2 Completed

75 enrolled 8 charts

Brain Neoplasms, Glioblastoma