Announcements Trials
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Phase

Phase 2 16Phase NA 5Phase 3 5Phase 1 4Phase EARLY_PHASE1 3Phase 4 3Phase 1/2 2

Status

Completed 2Withdrawn 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Lymphoid 4CNS 3Other hematologic neoplasm 2Genitourinary 1

Conditions

Rhabdoid Tumor 2Medulloblastoma 2Ependymoma 2Brain Neoplasms 2Neurotoxicity Syndromes 1Lymphoma 1Central Nervous System Neoplasms 1

Interventions

Temozolomide 17Magnetic Resonance Spectroscopy 16Radiotherapy 10Bevacizumab 7fluciclovine F-18 6Specimen Handling 6Topotecan 5Cyclophosphamide 5Biopsy 5fluorodopa F 18 4abemaciclib 4Vincristine 4Surgical Procedures, Operative 4Ketoconazole 4Irinotecan 4Fluorodeoxyglucose F18 4Ferrosoferric Oxide 4ribociclib 3gallium Ga 68 dotatate 3etoposide phosphate 3Radiation 3Pemetrexed 3Nivolumab 3Methotrexate 3Mesna 3Everolimus 3Etoposide 3Carboplatin 3posaconazole 2poly ICLC 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Methotrexate × CNS × Clear all
NCT02905110 2025-03-25

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

The University of Texas Health Science Center, Houston

Phase EARLY_PHASE1 Completed
3 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT01737671 2018-01-19

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Completed
7 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT00734773 2012-05-18

Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Northwestern University

Phase EARLY_PHASE1 Withdrawn
CNSLymphoid

Lymphoma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

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