Clinical Trials

160 enrolled

Brain Neoplasms, Craniopharyngioma

NCT03286335 2026-04-15

Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy

100 enrolled

Phase NA Active not recruiting

Brain Neoplasms

NCT03281889 2026-03-19

Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation

20 enrolled

Brain Neoplasms

NCT04908709 2026-03-04

Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors

25 enrolled

Malignant Brain Glioma

NCT04278118 2026-02-17

HiPPI

70 enrolled

CNSEndocrine

Brain Neoplasms, Meningioma, Neurilemmoma, Pituitary Neoplasms, Nerve Sheath Neoplasms

NCT02179086 2026-01-14

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

606 enrolled

Glioblastoma

NCT03180268 2026-01-14

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Phase 3 Recruiting

163 enrolled

Meningioma

NCT02112617 2025-12-30

Phase II Study of Proton Radiation Therapy for Neuroblastoma

30 enrolled

Phase NA Active not recruiting

Neuroblastoma, Ganglioneuroblastoma

NCT01358058 2025-12-10

Proton Radiation Therapy for Gliomas

63 enrolled

Brain Neoplasms, Glioma

NCT01419067 2025-10-20

A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection

112 enrolled

Craniopharyngioma

NCT06831461 2025-09-16

PRIDE

156 enrolled

CNSEndocrine

Brain Neoplasms, Meningioma, Pituitary Neoplasms

NCT01063114 2025-08-13

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

Phase NA Completed

90 enrolled 11 charts

Brain Neoplasms, Medulloblastoma, Pinealoma

NCT03180502 2025-07-11

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

120 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT03778294 2025-07-03

18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy

43 enrolled 19 charts

Glioblastoma, Glioma

NCT01117844 2024-11-07

Proton Radiation For Meningiomas and Hemangiopericytomas

Phase 1/2 Completed

53 enrolled

Hemangiopericytoma, Meningioma

NCT02073968 2024-01-25

PAINT

35 enrolled 13 charts

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT00895622 2023-09-08

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

244 enrolled 15 charts

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT05549414 2023-07-10

PPTS

Phase NA Unknown

100 enrolled

CNSHead & Neck

Brain Neoplasms, Head and Neck Neoplasms

NCT03267836 2023-06-15

Neoadjuvant Avelumab and Hypofractionated Proton Radiation Therapy Followed by Surgery for Recurrent Radiation-refractory Meningioma

Phase 1 Terminated

9 enrolled

Meningioma

NCT01730950 2022-12-29

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

182 enrolled 19 charts

CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00669669 2022-05-18

O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas

Phase 1/2 Terminated

12 enrolled 13 charts

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT01024907 2020-12-10

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

Phase 1/2 Completed

23 enrolled