Clinical Trials

Medulloblastoma

NCT06894979 2026-05-15

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Phase 1 Recruiting

54 enrolled

Astrocytoma

NCT03550391 2026-05-12

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Phase 3 Recruiting

206 enrolled

Brain Neoplasms

NCT05382338 2026-05-05

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Phase 3 Recruiting

225 enrolled

Medulloblastoma

NCT03224104 2025-11-26

STEAM

71 enrolled 18 charts

Astrocytoma, Glioblastoma

NCT04402073 2025-10-23

PersoMed-I

Phase 2 Terminated

20 enrolled

Medulloblastoma

NCT03345095 2025-07-01

MIRAGE

749 enrolled 15 charts

Phase 3 Active not recruiting

Glioblastoma

NCT00392327 2025-06-13

Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET

379 enrolled 29 charts

Medulloblastoma

NCT00085735 2025-01-14

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

549 enrolled 32 charts

Medulloblastoma

NCT00003375 2024-07-09

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Phase 2/3 Completed

370 enrolled

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00114140 2024-07-08

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

136 enrolled 9 charts

Phase 3 Active not recruiting

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00626990 2023-09-11

CATNON

751 enrolled 18 charts

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00895622 2023-09-08

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

244 enrolled 15 charts

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT00080938 2023-06-29

Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer

26 enrolled 8 charts

CNSThoracic

Adenocarcinoma of Lung, Brain Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00003309 2023-06-22

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

33 enrolled

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

NCT00028678 2023-06-18

Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

45 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT01730950 2022-12-29

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

182 enrolled 19 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01062399 2022-06-09

RTOG 0913

Phase 1/2 Completed

279 enrolled 14 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00626730 2021-02-03

Radiation Therapy in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Grade II or Grade III Meningioma

Phase 2 Unknown

78 enrolled

Meningioma, Central Nervous System Neoplasms

NCT00006916 2020-10-26

Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Phase 2 Terminated

19 enrolled 4 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006386 2020-10-22

Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme

80 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006388 2020-10-22

Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme

77 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00031967 2020-10-22

Melatonin and Radiation Therapy in Treating Patients With Brain Metastases

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries

NCT00033280 2020-10-22

Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas

42 enrolled

Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00004259 2019-09-12

Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas

230 enrolled 14 charts

Astrocytoma, Glioma, Central Nervous System Neoplasms

NCT00027846 2019-08-07

Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma

378 enrolled 16 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00238264 2019-08-07

Radiation Therapy in Treating Young Patients With Gliomas

92 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT01233479 2019-04-01

Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiation Therapy and Chemotherapy

Phase NA Withdrawn

Central Nervous System Neoplasms, Rhabdoid Tumor

NCT00085098 2018-09-07

Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor

24 enrolled 9 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00002569 2018-06-18

Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma

299 enrolled

Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00047320 2018-02-14

Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors

104 enrolled 12 charts

Brain Neoplasms, Teratoma, Central Nervous System Neoplasms

NCT00068250 2018-02-07

Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Phase 1/2 Completed

60 enrolled 10 charts

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT00003119 2017-03-13

Surgery in Treating Children With Neuroblastoma

968 enrolled

Neuroblastoma

NCT00182819 2016-10-12

Radiation Therapy or Temozolomide in Treating Patients With Gliomas

709 enrolled

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00003417 2015-11-17

Computer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma Multiforme

Phase 1/2 Completed

40 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003625 2014-07-28

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma

7 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003846 2014-07-28

Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors

25 enrolled

Neuroblastoma, Central Nervous System Neoplasms

NCT00003935 2014-07-28

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

31 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003573 2014-07-25

Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma

53 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00005602 2014-02-21

Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas

13 enrolled

Central Nervous System Neoplasms

NCT00028795 2014-02-21

Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma

170 enrolled

Astrocytoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00017368 2014-02-13

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma

42 enrolled

Neuroblastoma

NCT00070200 2014-02-13

Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma

31 enrolled

Neuroblastoma

NCT00099125 2014-01-24

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

170 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00107471 2013-12-10

Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma

Phase 1/2 Terminated

7 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00002708 2013-11-19

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

333 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT00003203 2013-08-23

Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors

168 enrolled

Brain Neoplasms, Neuroblastoma, Central Nervous System Neoplasms

NCT00004188 2013-05-17

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma

495 enrolled

Neuroblastoma

NCT00017147 2013-01-30

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

183 enrolled