Clinical Trials Browser

NIH × Surgical Procedures, Operative × CNS × Clear all

NCT06325683 2026-05-26

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Phase 2 Suspended

Glioblastoma

NCT03018288 2025-08-08

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Phase 2 Terminated

90 enrolled 24 charts

Glioblastoma, Glioma

NCT06328036 2024-12-30

Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma

Phase 2 Withdrawn

Glioblastoma

NCT00238303 2014-05-23

Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Phase 2 Completed

103 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00003842 2013-12-18

IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma

Phase 1 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003859 2013-12-04

Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS

Phase 3 Completed

Central Nervous System Neoplasms

NCT00003788 2013-11-06

Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas

Phase 3 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003122 2013-08-26

Surgery in Treating Patients With Neuroblastoma

Phase 2 Unknown

Neuroblastoma

NCT00003410 2013-06-26

Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003876 2013-06-26

Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003574 2013-06-21

Radiation Therapy in Treating Patients With Progressive or Recurrent Malignant Brain Tumors

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00004262 2013-06-04

Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Gliosarcoma

NCT00110032 2013-01-16

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Phase 1 Terminated

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00430079 2013-01-16

Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma

Phase NA Terminated

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Glioma, Subependymal, Gliosarcoma