Clinical Trials

30 enrolled

Neuroblastoma

NCT00601003 2024-08-06

Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma

112 enrolled 10 charts

Phase 2 Active not recruiting

Medulloblastoma, Neuroblastoma

NCT02308527 2024-05-14

BEACON

225 enrolled

Phase EARLY_PHASE1 Terminated

Neuroblastoma

NCT03927274 2023-05-25

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

3 enrolled

Brain Neoplasms, Glioma

NCT00014443 2023-01-09

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

Phase 2 Terminated

5 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT03154996 2022-07-05

Chronic Convection Enhanced Delivery of Topotecan

5 enrolled

Phase 2 Not yet recruiting

Glioma, Recurrence

NCT05303727 2022-07-01

Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma

64 enrolled

Neuroblastoma

NCT01004874 2022-04-13

Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma

80 enrolled 11 charts

Glioblastoma, Glioma, Gliosarcoma

NCT02390843 2020-04-03

AflacST1402

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

13 enrolled

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

NCT02786719 2020-03-12

SPRING

Phase NA Completed

13 enrolled 13 charts

Neuroblastoma

NCT02684071 2020-01-10

Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

Phase 2 Terminated

3 enrolled

Familial ependymoma, Ependymoma, Medulloblastoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Meningeal Carcinomatosis

NCT01492673 2019-10-29

Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma

9 enrolled 9 charts

Phase EARLY_PHASE1 Terminated

Neuroblastoma, Sarcoma, Sarcoma, Ewing

NCT02500459 2019-03-01

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

9 enrolled

Phase EARLY_PHASE1 Withdrawn

Brain Neoplasms, Glioma, Neoplasms

NCT03193463 2019-03-01

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Glioma

NCT01576692 2018-11-15

Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma

34 enrolled

Neuroblastoma

NCT00109798 2017-09-19

Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma

Phase NA Withdrawn

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT01736800 2017-09-19

Phase II Trial of Chemotherapy With Temodar With Topotecan for CNS Metastasis of Solid Tumors

Phase 2 Withdrawn

Brain Neoplasms, Neoplasm Metastasis

NCT00808899 2017-05-30

Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma

Phase 2 Terminated

4 enrolled 5 charts

Phase EARLY_PHASE1 Completed

Neuroblastoma

NCT02278510 2017-03-31

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

3 enrolled

CNSLymphoid

Glioma, Lymphoma, Follicular

NCT03042429 2017-02-06

NB2004-HR

Phase 3 Completed

360 enrolled

Neuroblastoma

NCT00960739 2016-08-08

MIITOP

30 enrolled

Neuroblastoma

NCT00918320 2016-01-26

TOTEM2

129 enrolled

Brain Neoplasms, Neuroblastoma

NCT01342237 2013-11-19

Tandem High Dose Chemotherapy and Autologous Stem Cell Rescue for High Risk Pediatric Brain Tumors

Phase 2 Unknown

33 enrolled

Brain Neoplasms

NCT00610571 2013-10-25

Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas

62 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00002515 2013-06-24

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

CNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther solid neoplasmSarcoma

Testicular Germ Cell Tumor, Burkitt Lymphoma, Chondrosarcoma, Fibrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Sarcoma, Osteosarcoma, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Dendritic Cell Sarcoma, Interdigitating, Desmoplastic Small Round Cell Tumor

NCT00040872 2013-03-07

Multiple Therapies in Treating Patients With Advanced Neuroblastoma

Neuroblastoma

NCT00002986 2013-02-20

Chemotherapy in Treating Patients With Recurrent Malignant Glioma

36 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00025311 2012-11-09

Topotecan in Treating Patients With Recurrent, Progressive, or Refractory Cancer That is Metastatic to the Lining Around the Brain

Central Nervous System Neoplasms, Meningeal Carcinomatosis

NCT00674674 2012-05-15

PBTC-019

22 enrolled

Meningitis, Meningeal Carcinomatosis

NCT00002814 2011-10-27

Combination Chemotherapy for Patients With Brain Cancer

20 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00541138 2011-09-21

Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors

50 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Neoplasm Metastasis, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00186849 2009-05-20

Therapy for Children With Advanced Stage High Risk Neuroblastoma

30 enrolled

Neuroblastoma

NCT00135135 2008-06-03

Therapy for Children With Neuroblastoma

23 enrolled