Announcements Trials
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Phase

Phase 1 7Phase 2 3Phase 4 1Phase 3 1

Status

Completed 3

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 8Myeloid 5Gastrointestinal 5Head & Neck 4Lymphoid 3CNS 3Thoracic 2Other solid neoplasm 2Dermatologic 2Tumor-Agnostic 1Sarcoma 1Gynecologic 1Genitourinary 1Classical hematology 1Breast 1

Conditions

Glioblastoma 3Brain Neoplasms 3Glioma 2Neurologic Manifestations 1Neoplasms, Neuroepithelial 1Gliosarcoma 1Diffuse Intrinsic Pontine Glioma 1Astrocytoma 1

Interventions

Temozolomide 258Radiotherapy 147Bevacizumab 142Etoposide 68Cyclophosphamide 68Carboplatin 66Magnetic Resonance Spectroscopy 58Irinotecan 53Cisplatin 52Vincristine 45Filgrastim 43pembrolizumab 40Radiosurgery 36Nivolumab 36Radiation 34Topotecan 31Doxorubicin 30Specimen Handling 29sargramostim 28Lomustine 27Erlotinib Hydrochloride 27Peripheral Blood Stem Cell Transplantation 25Carmustine 25Thiotepa 24Everolimus 23Chemotherapy, Adjuvant 23Surgical Procedures, Operative 22Isotretinoin 22Ipilimumab 22Melphalan 21

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 2 × Valproic Acid × CNS × Clear all
NCT01817751 2024-07-17

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

Virginia Commonwealth University

Phase 2 Completed
47 enrolled 13 charts
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neurologic Manifestations

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Baylor College of Medicine

Phase 2 Completed
38 enrolled 53 charts
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT00302159 2016-08-18

Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
43 enrolled 14 charts
CNS

Brain Neoplasms, Glioblastoma

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