Announcements Trials
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Phase

Phase 2 3Phase 1 2Phase EARLY_PHASE1 1

Status

Completed 3Terminated 2Recruiting 1

Sponsor Class

OTHER 3INDUSTRY 3

Study Type

Interventional 6

Sponsor

Cancer Type

Thoracic 19CNS 6Lymphoid 4Gastrointestinal 4Tumor-Agnostic 3Other hematologic neoplasm 3Sarcoma 2Plasma cell 2Dermatologic 2Head & Neck 1Endocrine 1

Conditions

Neuroblastoma 3Neoplasms 2Lymphoma, Large-Cell, Anaplastic 2Granuloma, Plasma Cell 2Glioblastoma 2Brain Neoplasms 2Rhabdomyosarcoma 1Hematologic Neoplasms 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Temozolomide 610Radiotherapy 388Bevacizumab 254Magnetic Resonance Spectroscopy 203Cyclophosphamide 177Carboplatin 159Radiosurgery 146Etoposide 132Radiation 121Irinotecan 115Vincristine 114Cisplatin 102Filgrastim 100Specimen Handling 88Nivolumab 87pembrolizumab 82Lomustine 81Topotecan 73Surgical Procedures, Operative 73Doxorubicin 60Melphalan 59Carmustine 57sargramostim 53Radiotherapy, Intensity-Modulated 53Isotretinoin 53Peripheral Blood Stem Cell Transplantation 52Granulocyte Colony-Stimulating Factor 50Erlotinib Hydrochloride 50Everolimus 48Chemotherapy, Adjuvant 48

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Interventional × ceritinib × CNS × Clear all
NCT02559778 2026-04-28

PEDS-PLAN

Milton S. Hershey Medical Center

Phase 2 Recruiting
500 enrolled
CNS

Neuroblastoma

NCT02780128 2026-03-10

NEPENTHE

Children's Hospital of Philadelphia

Phase 1 Terminated
66 enrolled
CNS

Neoplasms, Neuroblastoma

NCT02605746 2020-12-11

Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis

St. Joseph's Hospital and Medical Center, Phoenix

Phase EARLY_PHASE1 Completed
10 enrolled
CNS

Brain Neoplasms, Glioblastoma

NCT01742286 2020-06-09

Phase I Study of LDK378 in Pediatric, Malignancies With a Genetic Alteration in Anaplastic Lymphoma Kinase (ALK)

Novartis

Phase 1 Completed
83 enrolled 30 charts
CNSLymphoidPlasma cellSarcoma

Granuloma, Plasma Cell, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Lymphoma, Large-Cell, Anaplastic

NCT02336451 2020-04-21

Ascend-7

Novartis

Phase 2 Completed
156 enrolled 39 charts
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT02465528 2019-12-27

Ceritinib Rare Indications Study in ALK+ Tumors

Novartis

Phase 2 Terminated
22 enrolled 16 charts
CNSLymphoidOther hematologic neoplasmPlasma cell

Glioblastoma, Granuloma, Plasma Cell, Lymphoma, Large-Cell, Anaplastic, Hematologic Neoplasms

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