Announcements Trials
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Phase

Phase 2 3Phase 3 1Phase 1/2 1Phase 1 1

Status

Completed 6

Sponsor Class

INDUSTRY 6NIH 1

Study Type

Interventional 6

Sponsor

Cancer Type

Lymphoid 11Thoracic 8CNS 6Gastrointestinal 4Genitourinary 3Breast 3Gynecologic 2Tumor-Agnostic 1Sarcoma 1Plasma cell 1Other hematologic neoplasm 1Dermatologic 1

Conditions

Glioblastoma 4Glioma 2Neoplasms 1Gliosarcoma 1Brain Neoplasms 1

Interventions

Temozolomide 123Radiotherapy 47Bevacizumab 46Lomustine 25Radiation 20Nivolumab 17Irinotecan 16Carboplatin 16Cyclophosphamide 14Granulocyte-Macrophage Colony-Stimulating Factor 13pembrolizumab 11dabrafenib 10Trastuzumab 10Surgical Procedures, Operative 10Capecitabine 10paclitaxel-Angiopep-2 conjugate 8TIC10 compound 8Paclitaxel 8Gemcitabine 8Carmustine 8trametinib 7Topotecan 7IL13-PE38 7Everolimus 7Drug Therapy 7Aminolevulinic Acid 7AZD 6244 73-Iodobenzylguanidine 7fludarabine 6enzastaurin 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
INDUSTRY × enzastaurin × CNS × Clear all
NCT00586508 2020-09-24

Trial of Enzastaurin and Bevacizumab in Participants With Recurrent Malignant Gliomas

Eli Lilly and Company

Phase 2 Completed
81 enrolled 11 charts
CNS

Glioblastoma

NCT00402116 2020-08-06

Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients

Eli Lilly and Company

Phase 1/2 Completed
72 enrolled 19 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT00295815 2019-09-12

Enzastaurin Versus Lomustine in Glioblastoma

Eli Lilly and Company

Phase 3 Completed
397 enrolled
CNS

Glioblastoma

NCT00509821 2019-04-05

Enzastaurin Before and Concomitant With Radiation, Followed by Enzastaurin in Participants With Newly Diagnosed Glioblastoma

Eli Lilly and Company

Phase 2 Completed
60 enrolled 11 charts
CNS

Glioblastoma

NCT01445119 2013-08-28

A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas

Eli Lilly and Company

Phase 1 Completed
58 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms

NCT00190723 2007-01-26

A Study of LY317615 in Patients With Brain Tumors

Eli Lilly and Company

Phase 2 Completed
120 enrolled
CNS

Glioma

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