Announcements Trials
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Phase

Phase 2 2Phase 1/2 2Phase 1 1

Status

Completed 5

Sponsor Class

OTHER 3INDUSTRY 2

Study Type

Interventional 5

Sponsor

Cancer Type

Tumor-Agnostic 9CNS 5Genitourinary 4Gastrointestinal 4Thoracic 2Gynecologic 2Breast 2Other solid neoplasm 1NET 1Head & Neck 1Endocrine 1Dermatologic 1

Conditions

Brain Neoplasms 3Lung Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Neoplasm Metastasis 1Meningeal Carcinomatosis 1Head and Neck Neoplasms 1Glioblastoma 1Central Nervous System Neoplasms 1Breast Neoplasms, Male 1Breast Neoplasms 1

Interventions

Temozolomide 610Radiotherapy 388Bevacizumab 254Magnetic Resonance Spectroscopy 203Cyclophosphamide 177Carboplatin 159Radiosurgery 146Etoposide 132Radiation 121Irinotecan 115Vincristine 114Cisplatin 102Filgrastim 100Specimen Handling 88Nivolumab 87pembrolizumab 82Lomustine 81Topotecan 73Surgical Procedures, Operative 73Doxorubicin 60Melphalan 59Carmustine 57sargramostim 53Radiotherapy, Intensity-Modulated 53Isotretinoin 53Peripheral Blood Stem Cell Transplantation 52Granulocyte Colony-Stimulating Factor 50Erlotinib Hydrochloride 50Everolimus 48Chemotherapy, Adjuvant 48

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × epothilone B × CNS × Clear all
NCT00328458 2025-05-02

EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients

Thomas Jefferson University

Phase 1 Completed
39 enrolled
CNSHead & Neck

Head and Neck Neoplasms, Central Nervous System Neoplasms

NCT00219297 2021-02-21

Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer

Novartis

Phase 2 Completed
50 enrolled
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00450866 2014-02-28

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Case Comprehensive Cancer Center

Phase 2 Completed
55 enrolled 12 charts
BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male, Meningeal Carcinomatosis

NCT00171834 2014-02-05

Dose Escalating Study of the Safety and Efficacy of Patupilone, q3w, in Patients With Non-small Cell Lung Cancer

Novartis

Phase 1/2 Completed
89 enrolled 20 charts
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00715013 2011-09-15

Patupilone (EPO 906) in Patients With Recurrent or Progressive Glioblastoma

University of Zurich

Phase 1/2 Completed
9 enrolled
CNS

Glioblastoma

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