Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 1/2 1

Status

Recruiting 2Active not recruiting 2

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 258Other hematologic neoplasm 143Plasma cell 10Myeloid 6Genitourinary 4Gastrointestinal 4CNS 4Thoracic 3Classical hematology 3Tumor-Agnostic 2Dermatologic 2Breast 2NET 1Head & Neck 1Endocrine 1

Conditions

Glioblastoma 2Brain Neoplasms 2Primary Central Nervous System Lymphoma (PCNSL) 1Neurologic Manifestations 1Neuroectodermal Tumors, Primitive 1Medulloblastoma 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma 1Ependymoma 1Central Nervous System Neoplasms 1

Interventions

Temozolomide 623Radiotherapy 411Bevacizumab 257Magnetic Resonance Spectroscopy 227Cyclophosphamide 179Radiosurgery 163Carboplatin 160Etoposide 132Radiation 129Vincristine 115Irinotecan 115Cisplatin 103Filgrastim 100Specimen Handling 90Nivolumab 88pembrolizumab 84Surgical Procedures, Operative 83Lomustine 83Topotecan 73Doxorubicin 61Melphalan 59Carmustine 57Radiotherapy, Intensity-Modulated 56sargramostim 53Isotretinoin 53Peripheral Blood Stem Cell Transplantation 52Granulocyte Colony-Stimulating Factor 51Chemotherapy, Adjuvant 51Blood Specimen Collection 51Erlotinib Hydrochloride 50

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
ibrutinib × CNS × Clear all
NCT07082868 2026-05-06

A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)

Memorial Sloan Kettering Cancer Center

Phase 1 Recruiting
26 enrolled
CNSLymphoid

Primary Central Nervous System Lymphoma (PCNSL)

NCT05106296 2026-01-09

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Augusta University

Phase 1 Recruiting
37 enrolled
CNS

Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT03535350 2025-09-30

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Case Comprehensive Cancer Center

Phase 1 Active not recruiting
36 enrolled
CNS

Brain Neoplasms, Glioblastoma

NCT04446962 2025-09-25

LOC-R01

Institut Curie

Phase 1/2 Active not recruiting
118 enrolled
CNSLymphoid

Lymphoma, Neurologic Manifestations, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms

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