NCT07491211 2026-03-27
Osimertinib Combined With Intracranial SRT for EGFR-Mutant NSCLC With Symptomatic Brain Metastases
Fudan University
Active not recruiting
Clinical Trials
11 trialsNCT06304441 2025-09-29
Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer
Guangzhou Medical University
Phase NA Recruiting
NCT04233021 2025-02-03
ORBITAL
Intergroupe Francophone de Cancerologie Thoracique
Phase 2 Completed
NCT03732352 2024-11-12
18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma
Jonsson Comprehensive Cancer Center
Phase 2 Completed
NCT03769103 2024-10-31
Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC
British Columbia Cancer Agency
Phase 2 Active not recruiting
NCT05120960 2024-04-17
A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors
M.D. Anderson Cancer Center
Phase 1 Withdrawn
NCT06319950 2024-03-20
High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases
Taizhou Hospital
Phase 2 Not yet recruiting
NCT02736513 2021-09-02
Intracranial Activity of AZD9291 (TAGRISSO) in Advanced EGFRm NSCLC Patients With Asymptomatic Brain Metastases
Soroka University Medical Center
Phase 2 Unknown
NCT04425681 2020-06-11
OWBLM
Second Affiliated Hospital of Nanchang University
Phase 2 Unknown
NCT04148898 2019-11-04
OWONBNSCLCLM
Second Affiliated Hospital of Nanchang University
Phase 2 Unknown
NCT02972333 2016-11-23
Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M
Shandong Cancer Hospital and Institute
Phase 3 Unknown