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Phase

Phase 1 3Phase 2 1Phase 1/2 1

Status

Completed 9Terminated 5Active not recruiting 4Withdrawn 1Unknown 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Dermatologic 8CNS 5Lymphoid 4Gynecologic 3Breast 3Gastrointestinal 2Thoracic 1Sarcoma 1Head & Neck 1Genitourinary 1

Conditions

Glioblastoma 3Glioma 2Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Medulloblastoma 1Lymphoma, Follicular 1Gliosarcoma 1Central Nervous System Neoplasms 1Astrocytoma 1

Interventions

Temozolomide 80Radiotherapy 41Bevacizumab 35Radiosurgery 23Magnetic Resonance Spectroscopy 20Cyclophosphamide 17Radiation 14Irinotecan 13Carboplatin 12Topotecan 11Nivolumab 11Lomustine 11Filgrastim 10Everolimus 10Etoposide 10Erlotinib Hydrochloride 10pembrolizumab 9Radiotherapy, Intensity-Modulated 9Ipilimumab 9Granulocyte Colony-Stimulating Factor 8Carmustine 8antineoplaston AS 2-1 7antineoplaston A10 7Surgical Procedures, Operative 7Mental Status and Dementia Tests 7Isotretinoin 7Granulocyte-Macrophage Colony-Stimulating Factor 7sargramostim 6Vincristine 6TPI-287 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Terminated × poly ICLC × CNS × Clear all
NCT02924038 2024-06-14

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

University of California, San Francisco

Phase 1 Terminated
14 enrolled 10 charts
CNSLymphoid

Astrocytoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT03422094 2021-10-27

Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Washington University School of Medicine

Phase 1 Terminated
3 enrolled
CNS

Glioblastoma

NCT00052715 2018-07-18

Poly-ICLC

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated
31 enrolled 8 charts
CNSSarcoma

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02332889 2018-05-04

Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs

University of Louisville

Phase 1/2 Terminated
1 enrolled 6 charts
CNS

Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT02510950 2017-11-17

Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma

Washington University School of Medicine

Phase 1 Terminated
1 enrolled
CNS

Glioblastoma

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