Clinical Trials Browser

Interventional × regorafenib × CNS × Clear all

NCT03970447 2026-06-03

GBM AGILE

Phase 2/3 Recruiting

Glioblastoma, Recurrence

NCT06275919 2026-05-13

MIRAGE

Phase 2 Recruiting

Meningioma

NCT06047379 2026-03-02

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Phase 1/2 Recruiting

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Central Nervous System Neoplasms, Small Cell Lung Carcinoma

NCT06095375 2026-01-09

REGOMA-2

Phase 1 Completed

Glioblastoma

NCT04051606 2025-06-05

Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma

Phase 2 Completed

Glioblastoma

NCT04704154 2025-04-18

A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

Phase 2 Completed

175 enrolled 20 charts

CNSGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Glioblastoma

NCT02085148 2024-04-22

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Phase 1 Completed

CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Hepatoblastoma

NCT03520842 2023-08-01

Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer

Phase 2 Completed

22 enrolled 20 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT02926222 2022-09-09

REGOMA

Phase 2 Completed

Glioblastoma