Announcements Trials
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Phase

Phase 1 3

Status

Completed 3

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 6Gynecologic 6Lymphoid 5Breast 5Other solid neoplasm 3CNS 3Tumor-Agnostic 2Thoracic 2Plasma cell 2Genitourinary 2Other hematologic neoplasm 1Myeloid 1Gastrointestinal 1

Conditions

Glioblastoma 2Ovarian Neoplasms 1Lymphoma 1Gliosarcoma 1Glioma 1Central Nervous System Neoplasms 1Breast Neoplasms 1

Interventions

Temozolomide 610Radiotherapy 388Bevacizumab 254Magnetic Resonance Spectroscopy 203Cyclophosphamide 177Carboplatin 159Radiosurgery 146Etoposide 132Radiation 121Irinotecan 115Vincristine 114Cisplatin 102Filgrastim 100Specimen Handling 88Nivolumab 87pembrolizumab 82Lomustine 81Topotecan 73Surgical Procedures, Operative 73Doxorubicin 60Melphalan 59Carmustine 57sargramostim 53Radiotherapy, Intensity-Modulated 53Isotretinoin 53Peripheral Blood Stem Cell Transplantation 52Granulocyte Colony-Stimulating Factor 50Erlotinib Hydrochloride 50Everolimus 48Chemotherapy, Adjuvant 48

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × ridaforolimus × CNS × Clear all
NCT01295632 2015-08-27

Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)

Merck Sharp & Dohme LLC

Phase 1 Completed
65 enrolled
BreastCNSGynecologic

Breast Neoplasms, Glioblastoma, Ovarian Neoplasms

NCT00087451 2015-08-19

Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)

Merck Sharp & Dohme LLC

Phase 1 Completed
11 enrolled
CNSSarcoma

Glioblastoma, Glioma, Gliosarcoma

NCT00704054 2015-02-13

A Multi-Center Phase I Study of Intravenous Deforolimus (AP23573, MK-8669) Administered QDX5 Every Other Week in Pediatric Patients With Advanced Solid Tumors (8669-028)(COMPLETED)

Merck Sharp & Dohme LLC

Phase 1 Completed
15 enrolled
CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

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