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1 trials

Recent Start date Enrollment

sotorasib × CNS × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 33 Other solid neoplasm 8 Gastrointestinal 6 Tumor-Agnostic 1 Sarcoma 1 Other 1 Gynecologic 1 Classical hematology 1 CNS 1

Conditions

Brain Neoplasms 1

Interventions

Temozolomide 620 Radiotherapy 409 Bevacizumab 254 Magnetic Resonance Spectroscopy 223 Cyclophosphamide 178 Radiosurgery 162 Carboplatin 160 Etoposide 132 Radiation 128 Vincristine 115 Irinotecan 115 Cisplatin 103 Filgrastim 100 Specimen Handling 89 Nivolumab 88 pembrolizumab 83 Surgical Procedures, Operative 83 Lomustine 82 Topotecan 72 Doxorubicin 60 Melphalan 59 Carmustine 57 Radiotherapy, Intensity-Modulated 55 sargramostim 53 Isotretinoin 53 Peripheral Blood Stem Cell Transplantation 52 Granulocyte Colony-Stimulating Factor 51 Chemotherapy, Adjuvant 51 Erlotinib Hydrochloride 50 Blood Specimen Collection 49

Date Range

30 days 90 days 1 year All

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NCT06807619 2025-05-22

A Study of Sotorasib in People With Brain Tumors

Memorial Sloan Kettering Cancer Center

Phase 1 Recruiting

Brain Neoplasms

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