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Phase

Phase 2 3Phase 1/2 2Phase 4 1Phase 3 1Phase 1 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 9Gastrointestinal 6Thoracic 2Other solid neoplasm 2Genitourinary 2CNS 2Sarcoma 1Gynecologic 1Dermatologic 1

Conditions

Breast Neoplasms 2Prostatic Neoplasms 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Glioma 1Fallopian Tube Neoplasms 1Brain Neoplasms 1Astrocytoma 1

Interventions

Temozolomide 102Radiotherapy 47Bevacizumab 33Carboplatin 23Irinotecan 20pembrolizumab 17Radiosurgery 16Nivolumab 16Radiation 14Cyclophosphamide 11Magnetic Resonance Spectroscopy 10fludarabine 8Trastuzumab 8Radiotherapy, Intensity-Modulated 8Carmustine 8Surgical Procedures, Operative 7Specimen Handling 7Pemetrexed 7Paclitaxel 7Interleukin-2 7Filgrastim 7Everolimus 7Erlotinib Hydrochloride 7temsirolimus 6Vorinostat 6Radiotherapy, Conformal 6Lomustine 6Ipilimumab 6Granulocyte-Macrophage Colony-Stimulating Factor 6Gemcitabine 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × trastuzumab deruxtecan × CNS × Clear all
NCT05417594 2026-06-02

CERTIS1

AstraZeneca

Phase 1/2 Recruiting
695 enrolled
BreastCNSGastrointestinalGenitourinaryGynecologic

Astrocytoma, Breast Neoplasms, Fallopian Tube Neoplasms, Glioma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT04538742 2025-12-08

DB-07

AstraZeneca

Phase 1/2 Active not recruiting
245 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms

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