Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 4Sarcoma 3Other solid neoplasm 3Gynecologic 3Other hematologic neoplasm 2CNS 2Lymphoid 1Genitourinary 1

Conditions

Medulloblastoma 2Wilms Tumor 1Testicular Neoplasms 1Sarcoma, Ewing 1Sarcoma 1Rhabdomyosarcoma 1Recurrence 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Meningeal Carcinomatosis 1Lymphoma, Large B-Cell, Diffuse 1Familial ependymoma 1Dendritic Cell Sarcoma, Interdigitating 1Burkitt Lymphoma 1Brain Neoplasms 1Astrocytoma 1

Interventions

Temozolomide 610Radiotherapy 388Bevacizumab 254Magnetic Resonance Spectroscopy 203Cyclophosphamide 177Carboplatin 159Radiosurgery 146Etoposide 132Radiation 121Irinotecan 115Vincristine 114Cisplatin 102Filgrastim 100Specimen Handling 88Nivolumab 87pembrolizumab 82Lomustine 81Topotecan 73Surgical Procedures, Operative 73Doxorubicin 60Melphalan 59Carmustine 57sargramostim 53Radiotherapy, Intensity-Modulated 53Isotretinoin 53Peripheral Blood Stem Cell Transplantation 52Granulocyte Colony-Stimulating Factor 50Erlotinib Hydrochloride 50Everolimus 48Chemotherapy, Adjuvant 48

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Interventional × trioctyl phosphine oxide × CNS × Clear all
NCT00638898 2025-03-20

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

City of Hope Medical Center

Phase 1 Completed
25 enrolled
CNSGenitourinarySarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00005811 2013-02-21

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

National Cancer Institute (NCI)

Phase 2 Completed
77 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Medulloblastoma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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