NCT07422363 2026-04-13
Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma
National Cancer Institute (NCI)
Phase 1 Not yet recruiting
Clinical Trials
34 trialsNCT07518654 2026-04-08
ThINKK-01
St. Justine's Hospital
Phase 1 Not yet recruiting
NCT07496073 2026-03-27
A Phase I, Single-arm, Open-label Clinical Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of CHT101 Cell Infusion in Adult Subjects With Recurrent or Progressive Malignant Primary Brain Tumors（CROWN）
Tianjin Medical University Cancer Institute and Hospital
Phase 1 Not yet recruiting
NCT07492316 2026-03-25
PNOC020 rMB
University of Florida
Phase 1 Not yet recruiting
NCT07464925 2026-03-20
A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma
Tetragon Biosciences Ltd
Phase 1 Not yet recruiting
NCT07481721 2026-03-19
APIC-RG
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Phase 1 Not yet recruiting
NCT07472790 2026-03-16
A Study on the Novel Oncolytic Virus Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma
Beijing Bio-Targeting Therapeutics Technology Co., Ltd
Phase 1 Not yet recruiting
NCT06502171 2026-03-12
NF113
University of Alabama at Birmingham
Phase 1 Not yet recruiting
NCT07457307 2026-03-09
INSIGHT MRL
NYU Langone Health
Phase 1 Not yet recruiting
NCT07454668 2026-03-06
Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases
Baptist Health South Florida
Phase 1 Not yet recruiting
NCT07455045 2026-03-06
A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Phase 1 Not yet recruiting
NCT07441707 2026-03-02
A Study to Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain Tumours
Ipsen
Phase 1 Not yet recruiting
NCT07438860 2026-02-27
Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG
Case Comprehensive Cancer Center
Phase 1 Not yet recruiting
NCT07076498 2026-02-25
Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation
M.D. Anderson Cancer Center
Phase 1 Not yet recruiting
NCT07422896 2026-02-20
Bvax
Northwestern University
Phase 1 Not yet recruiting
NCT07218367 2026-02-13
Phase I Trial of pH Resections of GBM at VA
VA Office of Research and Development
Phase 1 Not yet recruiting
NCT07211737 2026-02-06
NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma
Baylor College of Medicine
Phase 1 Not yet recruiting
NCT07390539 2026-02-05
B7-H3.CD28Z.CART in CNS Neoplasms
Dana-Farber Cancer Institute
Phase 1 Not yet recruiting
NCT07385846 2026-02-04
Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency
University of Cincinnati
Phase 1 Not yet recruiting
NCT07361705 2026-01-23
Zorifertinib With Osimertinib for NSCLC With Meningeal Progression
Alpha Biopharma (Jiangsu) Co., Ltd.
Phase 1 Not yet recruiting
NCT07358260 2026-01-22
B7-H3.CD28Z.CART in Solid Tumors
Dana-Farber Cancer Institute
Phase 1 Not yet recruiting
NCT06357377 2026-01-14
A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors
Neonc Technologies, Inc.
Phase 1 Not yet recruiting
NCT07331064 2026-01-09
GABRIEL
Medical College of Wisconsin
Phase 1 Not yet recruiting
NCT07254845 2025-11-28
A PROSPECTIVE, SINGLE-CENTERED, ASSESSOR-BLINDED STUDY TO EVALUATE THE CLINICAL EFFICACY OF THE PROPOSED CELL/TISSUE HISTOPATHOLOGY PROCESSOR CCELL (CONFOCAL FLUORESCENCE ENDOMICROSCOPY) FOR INTRAOPERATIVE DIAGNOSIS IN BRAIN TUMORS
VPIX Medical
Phase 1 Not yet recruiting
NCT04903795 2025-11-03
BRiTE
Duke University
Phase 1 Not yet recruiting
NCT07199413 2025-09-30
Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy: A Phase I Pilot Safety and Feasibility Study for Solid Tumor Patients With CNS Metastases
Medical College of Wisconsin
Phase 1 Not yet recruiting
NCT06455189 2025-08-13
Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas
Case Comprehensive Cancer Center
Phase 1 Not yet recruiting
NCT06867978 2025-03-10
PRECISION
VPIX Medical
Phase 1 Not yet recruiting
NCT06742593 2024-12-19
Study of MT027 in Patients with Brain, Meninges, and Spinal Cord Metastatic Solid Tumors
Suzhou Maximum Bio-tech Co., Ltd.
Phase 1 Not yet recruiting
NCT06737146 2024-12-17
Study of MT027 in Patients with Recurrent or Progressive High-grade Glioma
Suzhou Maximum Bio-tech Co., Ltd.
Phase 1 Not yet recruiting
NCT04933422 2024-08-21
CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM)
Crimson Biopharm Inc.
Phase 1 Not yet recruiting
NCT06524063 2024-07-29
Targeted Survivin DC Cell Injection for the Treatment of GBM
Beijing Tricision Biotherapeutics Inc
Phase 1 Not yet recruiting
NCT06132438 2023-11-15
Immunotherapy Targeting of Cytomegalovirus Antigens in Glioblastoma
The University of New South Wales
Phase 1 Not yet recruiting
NCT05095441 2022-10-12
A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive Glioblastoma
ImmVira Pharma Co. Ltd
Phase 1 Not yet recruiting