Clinical Trials Browser

Phase 1 × Unknown × CNS × Clear all

NCT01107522 2025-09-09

Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas

Phase 1 Unknown

Glioblastoma, Glioma

NCT05868083 2024-02-23

The Safety and Efficacy of SNC-109 CAR-T Cells Therapy the Recurrent Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT03582514 2023-11-18

POBIG

Phase 1 Unknown

Glioblastoma

NCT05929456 2023-07-03

MIRROR

Phase 1 Unknown

Glioblastoma, Glioma

NCT05844605 2023-05-06

PREHABILITA

Phase 1 Unknown

Brain Neoplasms

NCT01672463 2023-03-29

OKN-007

Phase 1 Unknown

Glioma

NCT05782959 2023-03-24

Phase 1 Study of BCD-245 in Subjects With Neuroblastoma

Phase 1 Unknown

Neuroblastoma

NCT05737368 2023-02-21

Treatment of Recurrent Glioblastoma With Fractionated Radiotherapy Combined With Cadonilimab

Phase 1 Unknown

Glioblastoma

NCT04642937 2023-01-27

Study of CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT05700955 2023-01-26

Neoadjuvant Chemoimmunotherapy in Recurrent Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT05540873 2023-01-06

A Clinical Study of IL13Rα2 Targeted CAR-T in Patients With Malignant Glioma (MAGIC-I)

Phase 1 Unknown

Glioma

NCT04385173 2022-12-28

Pilot Study of B7-H3 CAR-T in Treating Patients With Recurrent and Refractory Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT03722342 2022-08-17

TTAC-0001 and Pembrolizumab Combination phase1b Trial in Recurrent Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT02285959 2022-08-10

Super-Selective Intraarterial Intracranial Infusion of Bevacizumab (Avastin) for Glioblastoma Multiforme

Phase 1 Unknown

Glioblastoma

NCT02013336 2022-03-31

Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

Phase 1 Unknown

Neuroblastoma, Recurrence, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT05201326 2022-01-21

Irinotecan And Bevacizumab Combined With Re-radiotherapy in Recurrent Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT05131763 2021-11-23

NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors

Phase 1 Unknown

CNSGastrointestinal

Colonic Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Medulloblastoma

NCT05108012 2021-11-22

Nk Cell Therapy for Recurrent Glioblastoma Multiform Patients

Phase 1 Unknown

Glioblastoma

NCT05107037 2021-11-04

A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of TQ-B3234 in Patients With Type I Neurofibromatosis

Phase 1 Unknown

Neurofibromatoses

NCT05063682 2021-10-01

CARTREMENDOUS

Phase 1 Unknown

Glioblastoma, Glioma

NCT04943718 2021-06-29

Personalized Vaccine for Patients With Recurrent Malignant Glioma

Phase 1 Unknown

Glioma

NCT03423992 2021-06-15

Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas

Phase 1 Unknown

Glioma, Recurrence

NCT04906473 2021-05-28

Safety,Tolerability, Pharmacokinetic,Pharmacodynamics and Efficacy of KY100001 in Patients With Advanced Solid Tumors

Phase 1 Unknown

Glioma

NCT03463733 2020-10-08

HUTMZ

Phase 1 Unknown

Glioblastoma, Glioma

NCT04550663 2020-09-23

NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors

Phase 1 Unknown

CNSGastrointestinal

Glioma, Carcinoma, Hepatocellular, Colorectal Neoplasms

NCT03734913 2020-07-22

A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors

Phase 1 Unknown

CNSDermatologicEndocrineNETThoracic

Carcinoma, Basal Cell, Glioblastoma, Medulloblastoma, Neuroendocrine Tumors, Small Cell Lung Carcinoma

NCT03231501 2020-06-16

HMPL-813 in Treating Patients With Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT03914768 2020-06-12

Immune Modulatory DC Vaccine Against Brain Tumor

Phase 1 Unknown

Diffuse Intrinsic Pontine Glioma, Glioblastoma

NCT04414020 2020-06-04

Cytoprotective Effect and Clinical Outcome of Perioperative Proesterone in Brain Tumors

Phase 1 Unknown

Brain Neoplasms

NCT04178057 2019-11-27

Phase I Clinical Study of GB222 to Evaluate the Safety, Tolerability and PK Profiles.

Phase 1 Unknown

Brain Neoplasms

NCT03392545 2019-07-11

InSituVac1

Phase 1 Unknown

Glioblastoma, Glioma

NCT03687034 2019-02-26

A Study of the Safety and Pharmacokinetics of BRCX014 in Patients With Glioblastoma

Phase 1 Unknown

Glioblastoma

NCT03638765 2018-08-20

Dendritic Cell Therapy for Brain Metastases From Breast- or Lung Cancer

Phase 1 Unknown

Brain Neoplasms

NCT03631836 2018-08-17

MARELLE01

Phase 1 Unknown

Glioblastoma

NCT02345824 2018-06-07

Early-Phase Study to Assess Inhibitor Ribociclib in Patients With Recurrent Glioblastoma or Anaplastic Glioma

Phase 1 Unknown

Glioblastoma, Glioma

NCT00052624 2018-05-15

Immunotoxin Therapy in Treating Children With Progressive or Recurrent Glioblastoma Multiforme or Anaplastic Astrocytoma

Phase 1 Unknown

Astrocytoma, Central Nervous System Neoplasms

NCT02840123 2018-03-02

Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines

Phase 1 Unknown

Diffuse Intrinsic Pontine Glioma

NCT02149459 2017-10-27

SMC 0712-13

Phase 1 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Insulin Resistance, Ketosis

NCT02672995 2017-08-18

Fractionated Stereotactic Radiosurgery With Concurrent Bevacizumab for Brain Metastases: A Phase I Dose-escalation Trial

Phase 1 Unknown

Brain Neoplasms

NCT02937844 2016-10-19

Pilot Study of Autologous Chimeric Switch Receptor Modified T Cells in Recurrent Glioblastoma Multiforme

Phase 1 Unknown

Glioblastoma

NCT02457650 2016-08-03

T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies

Phase 1 Unknown

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicPlasma cellSarcomaThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Synovial

NCT02844062 2016-07-26

Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme

Phase 1 Unknown

Glioblastoma

NCT01972750 2016-04-19

TKI258

Phase 1 Unknown

Glioblastoma, Recurrence

NCT02740933 2016-04-15

Demeclocycline Fluorescence for Intraoperative Delineation Brain Tumors

Phase 1 Unknown

Brain Neoplasms

NCT00083096 2015-02-10

Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas

Phase 1 Unknown

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00516607 2015-02-10

Enzastaurin and Temozolomide in Treating Patients With Primary Gliomas

Phase 1 Unknown

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT02331693 2015-01-06

CAR T Cells in Treating Patients With Malignant Gliomas Overexpressing EGFR

Phase 1 Unknown

Glioma

NCT02084927 2014-03-12

Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery

Phase 1 Unknown

Meningioma, Neurologic Manifestations

NCT00003842 2013-12-18

IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma

Phase 1 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00101309 2013-12-18

Vaccine Therapy and Interleukin-2 in Treating Young Patients With Relapsed or Refractory Ewing's Sarcoma or Neuroblastoma

Phase 1 Unknown

Neuroblastoma, Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral