Announcements Trials
Browse Landscape

Phase

Phase NA 32Phase 2 7Phase 3 5Phase 1 4Phase 1/2 3Phase 2/3 1

Status

Recruiting 3Not yet recruiting 2Unknown 1Completed 1

Sponsor Class

OTHER 1049INDUSTRY 232NIH 181NETWORK 72OTHER_GOV 7UNKNOWN 4FED 2

Study Type

Interventional 7

Sponsor

Cancer Type

Gastrointestinal 149Thoracic 82Breast 76Gynecologic 34Lymphoid 30Head & Neck 26Other hematologic neoplasm 17Genitourinary 16Dermatologic 13Sarcoma 11Tumor-Agnostic 8CNS 7Other solid neoplasm 6Endocrine 6Plasma cell 5NET 5Myeloid 5Classical hematology 3Other neoplasm 1Other 1

Conditions

Meningeal Carcinomatosis 3Brain Neoplasms 3Carcinoma, Non-Small-Cell Lung 2Radiation Injuries 1Memory Disorders 1Glioblastoma 1Cognitive Dysfunction 1

Interventions

lithium sulfate 1Temozolomide 1Radiotherapy 1Radiosurgery 1Pemetrexed 1Lithium 1Atorvastatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Phase 2 × OTHER_GOV × CNS × Clear all
NCT05805631 2026-03-24

Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC

Taipei Veterans General Hospital, Taiwan

Phase 2 Recruiting
23 enrolled
CNSThoracic

Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT07100600 2025-08-11

Trastuzumab Rezetecan Combined With Radiotherapy Versus Trastuzumab Rezetecan in the Treatment of HER2-positive Advanced Breast Cancer With Brain Metastases

Henan Cancer Hospital

Phase 2 Recruiting
224 enrolled
CNS

Brain Neoplasms

NCT06971406 2025-05-14

FLAME-1

Henan Cancer Hospital

Phase 2 Not yet recruiting
100 enrolled
CNSThoracic

Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT06441045 2024-06-04

Double Dose of Third-generation EGFR-TKI Plus Intrathecal Pemetrexed Versus Double Dose of Third-generation EGFR-TKI in Patients With LM Progression Following the Treatment of Routine Dose of Third-generation EGFR-TKI

Fujian Cancer Hospital

Phase 2 Not yet recruiting
112 enrolled
CNS

Meningeal Carcinomatosis

NCT06051240 2024-04-12

LiBRA

Region Stockholm

Phase 2 Recruiting
84 enrolled
CNS

Brain Neoplasms, Memory Disorders, Radiation Injuries, Cognitive Dysfunction

NCT02029573 2017-08-18

ART

King Fahad Medical City

Phase 2 Completed
36 enrolled
CNS

Glioblastoma

NCT00484978 2007-06-12

Stereotactic Radiosurgery to the Resection Cavity Following Surgical Removal of Brain Metastasis

Tel-Aviv Sourasky Medical Center

Phase 2 Unknown
35 enrolled
CNS

Brain Neoplasms

Data powered by HemOnc (CC BY 4.0) Colophon âš¡